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Nanostructured Cu and Cu-Al alloys processed by high-pressure torsion were isochronally annealed to investigate the effects of the stacking fault energy (SFE) on strength and ductility. All metals exhibit a similar general trend that the strength decreases and the ductility improves with increasing annealing temperatures, and a notable enhancement of ductility was achieved only when the volume fraction of recrystallized grains exceeded similar to 80%. The strength-ductility synergy improves significantly with decreasing SFE. (C) 2011 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.