在水相体系中,利用铜催化一系列氨基醇类底物(1.2 mmol)与碘代芳烃(1.0 mmol)进行N-芳基化反应.由于氨基醇具有双齿配位及相转移催化能力,该反应利用氨基醇类底物自身的促进作用,在不使用外加配体与相转移催化剂的温和条件下以高收率获得了氨基醇N-芳基化产物(64％-93％).
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