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PVA 水凝胶化学性质稳定、无毒、生物相容性好、耐生物老化、吸水量高及易于加工,广泛应用于固定化载体、药物释放、组织工程等领域。综述了当前国内外聚乙烯醇水凝胶的制备方法最新研究进展,详细介绍了国内外关于聚乙烯醇水凝胶的力学性能、溶胀性能、细胞亲和性、智能化等改性方法的研究进展。最后展望了未来聚乙烯醇水凝胶功能化改性的研究方向和前景。

PVA hydrogel is a chemically stable,non-toxic,biocompatible,biological aging resistant,high wa-ter absorption and easy processing material,which is widely used in immobilized carrier,drug release,tissue enginee-ring.The preparation methods of polyvinyl alcohol hydrogel were reviewed and the recent studies of mechanical pro-perties,swelling properties,cell affinity,and intelligence about polyvinyl alcohol hydrogel were introduced in detail in this work.The research directions and prospects of functional modification of PVA hydrogel in the future are prospec-ted.

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