以离子液体为催化剂,由维生素E经两步酯化反应合成了聚乙二醇1000 (PEG1000)维生素E琥珀酸酯.以离子液体1-(N',N'-二甲胺乙基)-3-甲基咪唑四氟硼酸盐为催化剂、1,2-二氯乙烷为助溶剂、维生素E与琥珀酸酐摩尔比为1∶1.2,在80℃条件下反应4h,维生素E琥珀酸酯(TAS)的产率为90％.以1-丙磺酸基-3-甲基咪唑硫酸氢盐/甲苯为反应体系,TAS与PEG1000摩尔比为1∶2,在100℃下反应5h,PEG1000维生素E琥珀酸酯(TPGS)收率为91％.
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