中空二氧化硅(SiO2)微球具有特殊的内部空腔、吸附渗透性好、物质传递可控等优异性能,可储存负载并缓慢释放药物、香精、染料、菌素等客体分子,因此在药物缓释、医学成像、环境保护以及化妆品等领域有着广阔的应用前景.根据国内外研究进展,本文归纳对比了中空SiO2微球几种制备方法之间的优劣差异,着重阐述了其作为缓控释载体表现出的持久性和高效性,以及功能化的有机/无机杂化微球在响应性控释方面的优越性.并对中空SiO2微球作为新型缓控释载体的发展前景进行了展望.
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