利用体外实验方法(in vitro)以及XRD、SEM、FTIR、BET、ICP等手段研究了两种溶胶-凝胶生物活性玻璃的显微结构及其在模拟生理溶液(SBF)中的降解过程、表面反应产物和生物矿化机理.结果表明,两种生物活性玻璃都具有较高的生物活性,均具有由纳米尺寸颗粒相互连接而成的微孔结构和较大的比表面积,在模拟生理溶液(SBF)中浸泡后可形成表面类似天然骨中无机矿物的碳酸羟基磷灰石层(HCA),说明两者均具有较高的生物活性和生理环境相应特性.材料表面的硅酸凝胶层及其硅羟基团的形成对碳酸羟基磷灰石(HCA)微晶的成核有重要作用.
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