将介孔生物活性玻璃(MBG)与脱钙骨(DB)复合, 利用浸渍法制备出MBG/DB复合支架材料. 采用红外光谱(FTIR), 扫描电镜(SEM), X射线衍射(XRD), 电子万能材料试验机等方法对牛松质骨(CB)、DB、MBG/DB复合支架进行表征. 结果表明, CB经浸酸处理后制备的DB, 孔径大小在200~600μm范围内, 孔隙率约为71%, 抗压性能比CB明显降低(1.10±0.31)MPa, 而采用浸渍法制备的复合支架, 孔隙率降为40%左右, 而压缩强度明显提高(8.49± 2.14)MPa. 体外生物活性测试表明: 复合支架具有良好的生物活性.
The composite scaffolds (MBG/DB) were prepared successfully through immersing the mesoporous bioactive glass powders into the demineralized bones. The bovine cancellous bone, demineralized bone, composite scaffold were investigated and characterized by FTIR, SEM, XRD and universal electromechanical testing machine. The results show that the compressive strength of the demineralized bones is about (1.10±0.31)MPa, the porosity is about 71% and the pore size is in the range from 200 to 600μm. However, the porosity and the compressive strength of the composite scaffolds are decreased to 40% and increase markedly to (8.49±2.14)MPa, respectively. Meanwhile, the composite scaffolds show good bioactivity in vitro.
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