对莽吉柿(Pricarpium Garciniae Mangostanae)85%乙醇提取物进一步分离,得到8个双苯毗酮类化合物和1个蒽酮类化合物,经理化性质和NMR及MS谱学数据鉴定分别为α-倒捻子素-3,6-二乙酸酯(α-mangostin-3,6-diyl diacetate,Ⅰ),1,5,8-三9基-3-甲氧基-2,4-双-(3-甲基T-烯)双苯毗酮(8-hydroxycud-raxanthone G,Ⅱ),1,3-二羟基-6,7-二甲氧基-2,8-双-(3-甲基T-烯基)双苯毗酮(Cowaxanthone B,Ⅲ)、1,6-二羟基-3,5-二甲氧基-(3-甲基丁-2-烯基)双苯毗酮(Cowaxanthone A,Ⅳ),1,5-二羟基-4-(3-甲基丁-2-烯基)-6',6'-二甲基毗喃[2',3':3,2]双苯酮(trapezifolixanthone,Ⅴ),1,6-二轻基-6',6'-二甲基毗喃「2',3':7,8]-6",6'-二甲基毗喃[2",3":3,2」双苯毗酮(brasilixanthone B,Ⅵ),1,3,5-三羟基-(3-甲基丁-2-烯)-4-(1,1-二甲基-2-烯丙基)双苯毗酮(Allanxanthone A,Ⅶ),1,3,8-三羟基-甲氧基-,4-双-(3-甲基丁-2-烯)双苯毗酮(2,4-di-(3-methylbut-2-enyl)-1,3,8-trihydroxy-5-methoxyxanthone,Ⅷ),1,4,8-三羟基-6-甲基-3-甲氧基-9,10-蒽酮(1,4,8-trihydroxy-6-methyl-3-methoxy-9,10-anthraquinone,Ⅸ).其中化合物Ⅰ、Ⅴ、Ⅵ、Ⅶ、Ⅸ为首次从藤黄属植物中分离得到,化合物Ⅱ、Ⅲ、Ⅳ、Ⅷ为首次从该植物中分离得到.
参考文献
| [1] | Mahabusarakam W,Kuaha K,Wilairat P,et al.Prenylated Xanthones as Potential Antiplasmodial Substances[J].Planta Med,2006,72(10):912-915. |
| [2] | Shankaranarayan D,Gopalakrishnan C,Kameswaran L.Pharmacological Profile of Mangostin and Its Derivatives[J].Arch Int Pharmacodyn Ther,1979,239(2):257-269. |
| [3] | Suksamram S,Komutiban 0,Ratananukul P,et al.Cytotoxic Prenylated Xanthones from the Young Fruit of Garcinia Mangostana[J].Chem Pharm Bull(Tokyo),2006,54(3):301-305. |
| [4] | Dharmaratne H.Antibacterial Activity of alpha-Mangostin Against Vancomycin Resistant Enterococci (VRE)and Synergism with Antibiotics[J].Phytomedicine,2005,12(3):203-208. |
| [5] | Jung H A,Su B N,Keller W J,et al.Antioxidant Xanthones from the Pericarp of Garcinia mangostana(Mangosteen)[J].J Agric Food Chem,2006,54(6):2077-2082. |
| [6] | Panthong K,Pongcharoen W,Phongpaichit S,et al.Tetraoxygenated Xanthones from the Fruits of Garcinia cowa[J].Phytochemistry,2006,67(10):999-1004. |
| [7] | Seo E K,Wall M E,Wani M C,et al.Cytotoxic Constituents from the Roots of Tovomita brevistaminea[J].Phytochemistry,1999,52:669-674. |
| [8] | Marques V L,De Oliveira F M,Conserva L M,et al.Dichromenoxanthones from Tovomita Bra-siliensis[J].Phytochemistry,2000,55:815-818. |
| [9] | Nkengfack A E,Azebaze G A,Vardamides J C,et al.A Prenylated Xanthone from Allanblackia floribunda[J].Phytochemistry,2002,60:381-384. |
| [10] | Bennett G J,Lee H H,Lee L P.Synthesis of Minor Xanthones from Garcinia mangostana[J].J Nat Prod,1990,53(6):1463-1470. |
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