利用有机锡卤化物与有机酸在有机胺存在下反应合成了一系列离子型有机锡化合物,分子通式为[HNR3][(PhCH2)3Sn(μ2-SCH2COO)Cl]、[HNR3][(Ph3Sn)3(O2CCH2CO2)2]·CH3CH2OH和[HNR3][MeCy2ClSnO2CCH2CO2SnClCy2Me].化合物体外抗肿瘤、杀菌和杀螨活性测试结果表明,部分化合物具有很好的生物活性.[HNR3][(Ph3Sn)3(O2CCH2CO2)2]·CH3CH2OH和[HNR3][MeCy2ClSnO2CCH2CO2SnClCy2Me]配合物对人肺癌细胞株A-549、结肠癌细胞株HCT-8和肝癌细胞株Bel-7402的抑制率约为90%,[HNR3][MeCy2ClSnO2CCH2CO2SnClCy2Me]配合物对小麦赤霉、番茄早疫、芦笋茎枯、苹果轮纹、花生褐斑的杀死率均为100%,配合物[HNR3][MeCy2ClSnO2CCH2CO2SnClCy2Me]的杀螨活性致死率大于90%.
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