根据金纳米粒子等离子体共振吸收引起的溶液颜色变化,建立了一种快速、简便检测头孢唑啉的色度分析方法.方法线性范围为0.1～5.0 μmol/L,检测限为14 nmol/L.将该方法用于头孢唑啉钠粉针剂的分析,回收率在97.4％～100.2％之间,相对标准偏差小于6.1％.
参考文献
| [1] | Kumarasamy K K,Toleman M A,Walsh T R,et al.Emergence of a New Antibiotic Resistance Mechanism in India,Pakistan,and the UK:a Molecular,Biological,and Epidemiological Study[J].Lancet Infect Dis,2010,10 (9):597-602. |
| [2] | Chinese Pharmacopoeia Commission.Pharmacopoeia of The People's Republic of China-two[M].Beijing:China Medical Science Press,2010:206-208 (in Chinese).国家药典委员会.中华人民共和国药典-二部[M].2010年版.北京:中国医药科技出版社,2010:206-208. |
| [3] | Farthing C,Farthing D,Brophy D F,et al.High-Performance Liquid Chromatographic Determination of Cefepime and Cefazolin in Human Plasma and Dialysate[J].Chromatographia,2008,67 (5/6):365-368. |
| [4] | Baranowska I,Markowski P,Baranowski J.Simultaneous Determination of 11 Drugs Belonging to Four Different Groups in Human Urine Samples by Reversed-Phase High-Performance Liquid Chromatography Method[J].Anal Chira Acta,2006,570(1):46-58. |
| [5] | Lin C E,Chen H W,Lin E C,et al.Optimization of Separation and Migration Behavior of Cephalosporins in Capillary Zone Electrophoresis[J].J Chrornatogr A,2000,879(2):197-210. |
| [6] | Bebawy L I,EI Kelani K E,Fattah L A.Fluorimetric Determination of Some Antibiotics in Raw Material and Dosage Forms through Ternary Complex Formation with Terbium(Tb3+)[J].J Pharm Biomed Anal,2003,32 (6):1219-1225. |
| [7] | ZHANG Yuzhong,ZHAO Hong,YUAN Zhuobin.Electrochemical Behavior of Degradation Product of Cefazolin with Silver Microdisk Electrode and Its Application to Analytical Chemistry[J]. Chinese J Anal Chem,2002,30 (1):9-12 (in Chinese).张玉忠,赵红,袁倬斌.头孢唑啉降解产物在银亚微盘电极上的电化学行为及其测定[J].分析化学,2002,30(1):9-12. |
| [8] | XU Bianzhen,ZHAO Fenglin,TONG Shenyang.Spectrophotometric Determination of Cefazolin Sodium Based on Chargetransfer Reaction[J].J Instrum Anal,1998,17 (6):29-32 (in Chinese).徐变珍,赵凤林,童沈阳.头孢唑啉钠的荷移分光光度法测定[J].分析测试学报,1998,17(6):29-32. |
| [9] | ZHANG Deyi,MA Yongjun,ZHOU Min,et al.Flow Injection Chemiluminescence Determination of Cefazolin Sodium[J].Chinese J Anal Lab,2006,25(2):44-47(in Chinese).张德懿,马永钧,周敏,等.流动注射化学发光法测定针剂中的头孢唑啉钠[J].分析试验室,2006,25(2):44-47. |
| [10] | Ghosh S K,Pal T.Interparticle Coupling Effect on the Surface Plasmon Resonance of Gold Nanoparticles:from Theory to Applications[J].Chem Rev,2007,107(11):4797-4862. |
| [11] | PAN Hongcheng,JIANG Zhiliang,YUAN Weien,et al. Relationship Between Resonance Scattering and Resonance Absorbance of Gold Nanoparticles[J].Chinese J Appl Chem,2005,22(3):282-285(in Chinese).潘宏程,蒋治良,袁伟恩,等.金纳米粒子共振散射与共振吸收的关系[J].应用化学,2005,22(3):282-285. |
| [12] | Eustis S,El-Sayed M A.Why Gold Nanoparticles are More Precious than Pretty Gold:Noble Metal Surface Plasmon Resonance and Its Enhancement of the Radiative and Nonradiative Properties of Nanocrystals of Different Shapes[J].Chem Soc Rev,2006,35 (3):209-217. |
| [13] | Zhao W A,Brook M A,Li Y F.Design of Gold Nanoparticle-based Colorimetric Biosensing Assays[J].Chem Bio Chem,2008,9(15):2363-2371. |
| [14] | Yu Y Y,Chang S S,Lee C L,et al.Gold Nanorods:Electrochemical Synthesis and Optical Properties[J].J Phys Chem B,1997,101 (34):6661-6664. |
| [15] | Zhao W A,Chiuman W,Lam J C F,et al.Simple and Rapid Colorimetric Enzyme Sensing Assays Using Non-Crosslinking Gold Nanoparticle Aggregation[J].Chem Commun,2007,(36):3729-3731. |
| [16] | Xu X W,Wang J,Jiao K,et al.Colorimetric Detection of Mercury Ion (Hg2+) Based on DNA Oligonucleotides and Unmodified Gold Nanoparticles Sensing System with a Tunable Detection Range[J].Biosens Bioelectron,2009,24 (10):3153-3158. |
| [17] | Zhou Y,Wang S X,Zhang K,et al.Visual Detection of Copper(Ⅱ) by Azide-and Alkyne-Functionalized Gold Nanoparticles Using Click Chemistry[J].Angew Chem Int Ed,2008,47(39):7454-7456. |
| [18] | Lee J H,Wang Z D,Liu J W,et al.Highly Sensitive and Selective Colorimetric Sensors for Uranyl(UO2+2):Development and Comparison of Labeled and Label-Free DNAzyme-Gold Nanoparticle Systems[J].J Am Chem Soc,2008,130 (43):14217-14226. |
| [19] | LIU Chun,WU Tong,HUANG Chengzhi.Gold Nanoparticle Surface Energy Transfer and Its Application to Highly Selective and Sensitive Detection of Cysteine[J].Sci China Ser B-Chem,2010,40 (5):531-537 (in Chinese).刘春,吴同,黄承志.金纳米微粒表面能量转移及半胱氨酸的高灵敏度高选择性分析法[J].中国科学B辑:化学,2010,40(5):531-537. |
| [20] | Huang C C,Huang Y F,Cao Z H,et al.Aptamer-Modified Gold Nanoparticles for Colorimetric Determination of PlateletDerived Growth Factors and Their Receptors[J].Anal Chem,2005,77(17):5735-5741. |
| [21] | Li H X,Rothberg L.Colorimetric Detection of DNA Sequences Based on Electrostatic Interactions with Unmodified Gold Nanoparticles[J].PNAS,2004,101(39):14036-14039. |
| [22] | Zhang J,Wang L H,Pan D,et al.Visual Cocaine Detection with Gold Nanoparticles and Rationally Engineered Aptamer Structures[J].Small,2008,4 (8):1196-1200. |
| [23] | Liu Z D,Huang C Z,Li Y F,et al.Enhanced Plasmon Resonance Light Scattering Signals of Colloidal Gold Resulted from Its Interactions with Organic Small Molecules Using Captopril as an Example[J].Anal Chim Acta,2006,577 (2):244-249. |
| [24] | Qi W J,Wu D,Ling J,et al.Visual and Light Scattering Spectrometric Detections of Melamine with Polythymine-Stabilized Gold Nanoparticles Through Specific Triple Hydrogen-Bonding Recognition[J].Chem Commun,2010,46 (27):4893-4895. |
| [25] | Grabar K C,Freeman R G,Hommer M B,et al.Preparation and Characterization of Au Colloid Monolayers[J].Anal Chem,1995,67(4):735-743. |
| [26] | Jin R C,Wu G S,Li Z,et al.What Controls the Melting Properties of DNA-Linked Gold Nanoparticle Assemblies?[J].J Am Chem Soc,2003,125 (6):1643-1654. |
| [27] | Jain P K,Huang W Y,El-Sayed M A.On the Universal Scaling Behavior of the Distance Decay of Plasmon Coupling in Metal Nanoparticle Pairs:a Plasmon Ruler Equation[J].Nano Lett,2007,7 (7):2080-2088. |
| [28] | Storhoff J J,Lazarides A A,Mucic R C,et al.What Controls the Optical Properties of DNA-Linked Gold Nanoparticle Assemblies?[J].J Am Chem Soc,2000,122(19):4640-4650. |
| [29] | El-Shaboury S R,Saleh G A,Mohamed F A,et al.Analysis of Cephalosporin Antibiotics[J].J Pharm Biomed Anal,2007,45(1):1-19. |
| [30] | HU Changqin,YIN Lihui,LIANG Yaning.Physical and Chemical Characteristics of a New Cefazolin Sodium Hydrate Crystal[J].Acta Pharm Sin,2008,43(8):868-872(in Chainese).胡昌勤,尹立辉,朗雅宁.头孢唑林钠水合物新晶体及其理化特性的研究[J].药学学报,2008,43(8):868-872. |
| [31] | Mimura H,Gato K,Kitamura S,et al.Effect of Water Content on the Solid-State Stability in Two Isomorphic Clathrates of Cephalosporin:Cefazolin Sodium Pentahydrate (α Form) and FK041 Hydrate[J].Chem Pharm Bull,2002,50 (6):766-770. |
| [32] | Stephenson G A,Diseroad B A.Structural Relationship and Desolvation Behavior of Cromolyn,Cefazolin and Fenoprofen Sodium Hydrates[J].Int J Pharm,2000,198(2):167-177. |
| [33] | WU Jiehua.Crystallization Process of Cefazolin Sodium Pentahydrate[D].Tianjin:Tianjin University,2007 (in Chinese).武洁花.头孢唑啉钠结晶过程研究[D].天津:天津大学,2007. |
| [34] | Anacona J R,Alvarez P.Synthesis and Antibacterial Activity of Metal Complexes of Cefazolin[J].Transition Met Chem,2002,27 (8):856-860. |
| [35] | Thompson D W,Collins I R.Electrical Properties of the Gold-Aqueous Solution Interface[J].J Colloid Interface Sci,1992,152(1):197-204. |
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