在水相回流条件下,以芳香醛、5,5-二甲基-1,3-环己二酮(达米酮)和苯胺/对甲苯胺为原料,经过多组分一锅反应,合成了一系列N-取代吖啶二酮衍生物,收率在69％～90％之间.该过程以水作为溶剂,无有机溶剂污染,而且操作简单,后处理方便.
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