分别以3,5-二氯苯胺为原料,经N保护、硝化、水解以及以l,3,5-三氯-2,4,6-三硝基苯(TCTNB)为原料,经叔丁胺化,再在三氟乙酸中脱叔丁基2种方法合成了3,5-二氯-2,4,6-三硝基苯胺.与甲胺反应,合成了3,5-二甲氨基-2,4,6-三硝基苯胺,收率85％,再用混酸硝化合成了3,5-二甲硝胺基-2,4,6-三硝基苯胺的硝酸盐,收率70％.采用核磁共振、质谱、红外和元素分析等进行了结构表征.探讨了不同参数下TCTNB的氨化结果.优化的条件为:n(TCTNB)∶n(叔丁胺)=1∶2,CuO为催化剂,KHCO3为碱.
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