光动力治疗是一种非侵蚀性并具有一定靶向性的肿瘤治疗新方法.光动力治疗需要光敏剂、光和氧结合产生光动力反应.光敏剂是光动力治疗的关键和物质基础.本文概括介绍了已上市的和已被批准进入临床试验中的光敏剂,并根据其分子的骨架结构,将其分为分卟啉类、二氢卟吩(叶绿素)类和菌绿素/酞菁三类.同时从理想光敏剂应具备特点出发,探讨了研究中的光敏剂和光动力治疗的发展前景.
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