采用化学-物理交联法制备了聚乙烯醇/壳聚糖/纳米羟基磷灰石(PVA/CS/n-HA)复合水凝胶材料.通过对比其含水率、拉伸强度、红外光谱和TG谱图,探讨了PVA含量及戊二醛加入量对材料性能的影响.结果表明,m(PVA)∶m(CS+ n-HA) =5∶1,戊二醛质量分数为2％时,复合水凝胶材料具有较好的综合性能:含水率为82.0％、拉伸强度为2.14 MPa、断裂伸长率为343.26％;同步热分析表明,25～ 140℃,仅存在水分的蒸发,直至360℃材料才发生分解,说明材料的热稳定性良好;红外分析表明,CS与戊二醛发生了交联反应.
参考文献
| [1] | Maiolo A S,Amado M N,Gonzalez J S,et al.Development and Characterization of Poly (vinyl alcohol) Based Hydrogels for Potential Use as an Articular Cartilage Replacement[J].Mater Sci Eng C,2012,32 (6):1490-1495. |
| [2] | Yoon S D,Park M H,Byun H S.Mechanical and Water Barrier Properties of Starch/PVA Composite Films by Adding Nano-sized Poly(methylmethacrylate-co-acrylamide) Particles[J].Carbohydr Polym,2012,87 (1):676-686. |
| [3] | Zhang P Y,Li Y L,Fan L,et al.Modification of Chitosan Membrane with Poly(vinyl alcohol) and Biocompatibility Evaluation[J].Int J Biol Macromol,2012,50(3):658-663. |
| [4] | XU Caixia,CHEN Riyao,ZHENG Xi,et al.Preparation of PVA-CS/SA Bipolar Membrane and Its Application in Electrogeneration of Hydroxypivalic Acid[J].Chinese J Appl Chem,2008,25(3):317-321 (in Chinese).许彩霞,陈日耀,郑曦,等.PVA-SA/CS双极膜制备及在电解制备羟基新戊酸中的应用[J].应用化学,2008,25(3):317-321. |
| [5] | Diamond A D,Hsuj T.Correlation of Protein Partitioning in Aqueous Polymer Two-phase System[J].J Chromtogr A,1990,513:137-143. |
| [6] | WANG Xin,LIU Lingrong,ZHANG Qiqing.Etala Study on Nano-Hydroxyapatite-Chitosan Scaffold for Bone Tissue Engineering[J].Chinese J Reparative Reconstr Surg,2007,21 (2):120-124 (in Chinese).王新,刘玲蓉,张其清.纳米羟基磷灰石-壳聚糖骨组织工程支架的研究[J].中国修复重建外科杂志,2007,21(2):120-124. |
| [7] | GUAN Jing,GAO Ping,HUANG Shujie.Biocompatibility of Polyvinyl Alcohol Hydrogel[J].ChineseJ Clin Rehab Tissue Eng Res,2009,13(12):2227-2231(in Chinese).关静,高萍,黄姝杰.聚乙烯醇水凝胶的生物相容性评价[J].中国组织工程研究与临床康复,2009,13(12):2227-2231. |
| [8] | EzequielS C J,EdelF B S,AlexandraA P M,et al.Preparation and Characterization of Chitosan/poly (vinyl alcohol)Chemically Crosslinked Blends for Biomedical Applications[J].Carbohydr Polym,2009,76 (3):472-481. |
| [9] | Giri T K,Thakur A,Alexander A,et al.Modified Chitosan Hydrogels as Drug Delivery and Tissue Engineering Systems:Present Status and Applications[J].Acta Pharm Sin B,2012,2(5):439-449. |
| [10] | Alipour S M,Nouri M.Ehctrospinning of Poly (vinyl alcohol)-Water-soluble Quaternized Chitosan Derivative Blend[J].Carbohydr Res,2009,334(18):2496-2501. |
| [11] | OUYANG Junjun,ZHOU Li.Preparation and Properties of Porous β-Tricalcium Phosphate/Chitosan/Polyvinyl Alcohol Composite Hydrogel[J].Chinese J Appl Chem,2012,29(9):995-999(in Chinese).欧阳君君,周莉.多孔β-磷酸三钙/壳聚糖/聚乙烯醇复合水凝胶的制备与性能[J].应用化学,2012,29(9):995-999. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%