研究了L-脯氨酸制得的C2-对称二胺,与醋酸铜形成新的配合物,催化各种醛与硝基烷烃间的Henry反应.考察了反应温度、溶剂和催化剂用量对收率和反应速率的影响.研究结果表明,在室温下,以乙醇作为反应溶剂时,摩尔分数10％的二胺醋酸铜配合物能够有效地催化醛与硝基甲烷反应,生成相应的β-硝基醇,收率为60％ ～92％.醛与硝基乙烷的Henry反应产物具有非对映立体选择性.芳香醛参与Henry反应产物的非对映选择性高达24:1,但脂肪醛为底物时,此催化剂对Henry反应的非对映选择性不明显.
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