以黄体酮为原料,合成了4′-硝基苯亚甲基衍生物3,将其在SnCl2·2H2O/HCl体系中还原后得4′-氨基苯亚甲基衍生物4.还原时以乙酸乙酯为溶剂,还原剂SnCl2为底物5倍化学计量时产率达74％,为甾类氨基衍生物的合成提供了一种便利方法.
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