Brφnsted酸催化合成α-氨基膦酸酯

应用化学, 2014, 31(12): 1428-1433. doi: 10.3724/SP.J.1095.2014.40052

Brφnsted酸催化合成α-氨基膦酸酯

姚元勇 ^1, , 吴兰艳 ^2, , 舒华 ^3, , 唐帮成 ^4, , 薛伟 ^5,

1.铜仁学院生物与化学工程系,梵净山特色动植物资源重点实验室铜仁554300;贵州大学精细化工研究中心贵阳550025

2.铜仁学院生物与化学工程系,梵净山特色动植物资源重点实验室铜仁,554300

3.铜仁学院生物与化学工程系,梵净山特色动植物资源重点实验室铜仁,554300

4.铜仁学院生物与化学工程系,梵净山特色动植物资源重点实验室铜仁,554300

5.贵州大学精细化工研究中心贵阳550025

基金项目: 贵州省教育厅联合基金KY字[2011]005 Tongren Science and Technology Bureau Nature and Science Foundation(2014403) Guizhou Educational Ministry Science and Technology United Foundation(2011005) 铜仁市科技局自然科学基金[2014]40-3 贵州省教育厅“125”重大科技专项([2012]018) the Guizhou Educational Ministry "125" Key Science and Technology Project(2012018)

关键词： Brφnsted酸 , α-氨基膦酸酯 , 氢键作用 , 催化 , 磷氢化反应

Synthesis of α-Aminophosphonates by Brφnsted Acid Catalysis

Keywords： Brφnsted acid , α-aminophosphonate , hydrogen bonding interaction , catalysis , hydrophosphonylation

以芳香胺和肉桂醛为原料,合成的芳香族亚胺为亲电试剂,亚磷酸二乙酯或亚磷酸三乙酯为亲核试剂,在10％(摩尔分数)磷酸催化剂(Brφnsted acid)的作用下,通过催化剂与亲电试剂、亲核试剂之间共同形成的双氢键或单氢键的作用,成功地合成了α-氨基膦酸酯类化合物,收率可达到79％～85％.

参考文献

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