以双酚A(BPA)为模板分子,乙腈(ACN)为致孔剂,α-甲基丙烯酸为功能单体(MAA),乙二醇二甲基丙烯酸酯(EDMA)为交联剂,偶氮二异丁腈(AIBN)为引发剂,快速制备了双酚A分子印迹聚合物(MIP)萃取头.聚合反应在内径为530μm的毛细管中进行,微波聚合7 min.得到的双酚A分子印迹聚合物从毛细管中推出,在安培瓶中洗脱后再次插入毛细管中用于固相微萃取(SPME).在不同的模板分子和功能单体的比例(BPA/MAA)、NaC1浓度、萃取和解吸时间、pH值和解吸溶剂条件下考察了聚合物的萃取性能.选取结构类似物苯酚(P)、对羟基联苯(PP)和非结构类似物二聚氰胺(DCD),对MIP和非印迹聚合物(NIP)的选择性吸附性能进行了对比.所建立的SPME方法结合高效液相色谱法(HPLC)成功用于饮料中双酚A的检测.在优化的实验条件下,双酚A的线性范围为10～ 400μg/L,检出限(LOD)为0.45 μg/L,在矿泉水中的回收率为88.4％ ～ 102.8％.结果表明所建立的方法能够用于检测实际样品中的BPA,具有样品预处理简便、分析快速、检出限低和消耗低的优点.
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