邻苯二甲酸酯是应用最广泛的增塑剂，具有生殖、发育毒性及致癌性，是近年来食品污染的一个重要来源。该类化合物种类多、同系物和同分异构体性质接近、在基体中含量范围宽，高效样品前处理、高选择性分离和高灵敏检测、降低本底干扰等技术是食品中邻苯二甲酸酯类化合物准确测定面临的挑战。本文综述了液液萃取、液液微萃取、固相萃取、固相微萃取、基质固相萃取等传统及新型的提取与净化技术在食品样品分析中的应用，比较分析了气相色谱、液相色谱、串联质谱、高分辨质谱以及酶联免疫、离子迁移谱等快速检测技术的特点，并展望了发展趋势。
Phthalate esters are most widely used as plasticizers which have toxicity and carci-nogenicity. Phthalate esters are found as contaminants in many food products and they are a branch of compounds,homologues and isomers,which present similar structures and proper-ties. And the residue contents vary a lot in different matrices. Efficient sample pretreatment, highly selective separation mode,sensitive detection methods as well as reducing background interference are challenges for their determination in complex samples. In this paper,some sample pretreatment methods such as liquid-liquid extraction,liquid-liquid micro-extraction, solid phase extraction,solid phase micro-extraction,matrix solid-phase extraction and other traditional and new types of extraction and purification technology applied in the food samples are reviewed. The characteristics of analytical methods including gas chromatography ,liquid chromatography,tandem mass spectrometry, high resolution mass spectrometry, enzyme-linked immunoassay,and ion mobility spectrometry are also discussed.
参考文献
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| [2] | Wu, P.;Yang, D.;Zhang, L.;Shen, X.;Pan, X.;Wang, L.;Zhang, J.;Tan, Y.;Feng, L.;Ying, Y..Simultaneous determination of 17 phthalate esters in edible vegetable oils by GC-MS with silica/PSA-mixed solid-phase extraction[J].Journal of separation science,201221(21):2932-2939. |
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