The title compound 3 was synthesized from diethylguanidine nitrate (2) obtained from diethylamine, CaCN2 and HNO3. The mixture consisted of 0.5 mol 2, 0.55 mol acetonyl propionate,3 g benzyltriethylammonium chloride, and 44 g NaOH was refluxed for 4 hours to give 85 g 3, in yield 94.6%.
参考文献
| [1] | Stuart P S,Brian K S. S African,6 805 808,1970 |
| [2] | Joseph S, Jacques P, Dominique A. Eur Pat Appl Ep 552 084,1993 |
| [3] | Overberger C G,Kogon I C. J Am Chem Soc,1954,76:1879 |
| [4] | John T G,Alex M J,Teruko U M, et al. US 4 018771,1977 |
| [5] | Gagnon P E,Boivin J L,Boivin P A. et al. Can J Chem, 1958,36: 737 |
| [6] | Cyril U,Stefan T,Milan M, et al. Czech CS 202955,1982 |
| [7] | Gershon H,Grefig A, Clarke D D. J Heterocycl Chem, 1987,24 (1): 205 |
| [8] | HUANG Shu (黄枢).XIE Ru-Gang (谢如刚).TIAN Bao-Zhi (田宝芝)et al Auths (著).The Handbook of Organic Reagents Synthesis (有机合成试剂制备手册).Sichuan (四川): Sichuan University Press (四川大学出版社).1988：34 |
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