在pH=4.0的HCl-NaAc缓冲溶液中,盐酸苯海拉明(DPH)-硅钨杂多酸缔合微粒体系在295 nm处有1吸收峰,DPH浓度在0.50×10-6～8.0×10-6g/mL范围内与吸光度成良好线性关系,检出限(3σ)为0.1×10-6g/mL.该法用于测定片剂中DPH含量具有灵敏、简便、快速、准确、重复性好等特点,回收率为98%～102%,相对标准偏差RSD为0.9%～2.2%.共振散射光谱表明,该体系存在DPH-硅钨杂多酸缔合物微粒.
参考文献
| [1] | LI Zheng-Hua(李正化).Pharmaceutical Chemistry(药物化学)[M],3rd Edn(第3版).Beijing(北京):People'sPress(人民出版社),1993:290 |
| [2] | Pharmacopia Committee of P.R.China(中华人民共和国卫生部药典委员会).Pharmacopia of P.R.China(中华人民共和国药典)[M],2nd Edn(二部).Beijing(北京):People's Health Press(人民卫生出版社),1990:800 |
| [3] | QIAN Shu-De(钱树德).Chin J Pharm Anal(药物分析杂志)[J],1984,4:178 |
| [4] | ZHANG Zhi-Yao(张智耀),ZHANG Zhen-Liang(张贞良),ZHANG Shu-Run(张书润),et al.Chin J Pharm Anal(药物分析杂志)[J],1993,13:162 |
| [5] | XING Yu-Ren(邢玉仁).Chin J Pharm Ahal(药物分析杂志)[J],1991,11:186 |
| [6] | LANG Hui-Yun(郎惠云),WANG Hai-Tao(汪海涛),WANG Tian-Bao(王天宝),et al.J Aral Sci(分析科学学报)[J],2004,20(1):48 |
| [7] | AI Jun(艾军),WU Chuan-qong(吴传琼).Anal Test Acta(分析测试学报)[J],2001,25:62 |
| [8] | Liu S P,Feng P.MikrochimActa[J],2002,140(1):189 |
| [9] | Huang C Z,Li Y F.AnalChimActa[J],2003,500:105 |
| [10] | YUAN Wei-En(袁伟恩),JIANG Zhi-Liang(蒋治良).Anal Test Tech Instr(分析测试技术与仪器)[J],2004,10(4):193 |
| [11] | LIANG Ai-Hui(梁爱惠),JIANG Zhi-Liang(蒋治良),LI Zhen-Zhong(李振中),et al.Chin J Appl Chem(应用化学)[J],2004,22:1 217 |
| [12] | JIANG Zhi-Liang(蒋治良),JIANG Hong-Liu(江洪流),LIU Feng-Zhi(刘凤志).Chin JAppl Chem(应用化学)[J],2003,20(4):351 |
| [13] | JIANG Zhi-Liang(蒋治良),LIU Shao-Pu(刘绍璞),LIU Qing-Ye(刘庆业).Chin JAppl Chem(应用化学)[J],2002,19(1):22 |
| [14] | Tipparat P,Lapanatnoppakhun S,Jaknunee J,et al.J Pharm Biomed Anal[J],2002,30:105 |
| [15] | LI Dong-Hui(李东辉),YUE Jing-Li(岳京立),YU Qiu-Hong(于秋泓),et al.Chin J Anal Chem(分析化学)[J],2002,30:292 |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%