以S-(-)-乳酸甲酯、S-(-)-α-苯乙醇、(S)-(+)-仲丁醇为手性源,以N,N′-二环己基碳二亚胺(DCC)为缩水剂、4-二甲氨基吡啶为酰化催化剂,分别与上述3种不饱和酸进行酯化反应合成了新的手性不饱和酯类单体,用红外光谱、核磁共振及有机元素分析表征了产物结构. 以聚硅氧烷接枝手性单体,制备得到了手性固定相.
With methyl-S-(-)-lactate, S-(-)-α phenylethyl alcohol, (S)-(+)-2-butanol as the chiral pool, new chiral unsaturated esters were synthesized under the catalysis of N,N′-dicyclohexyl carbodimide(DCC) and 4-dimethylaminopyridines. The products were characterized by means of infrared, NMR and elemental analysis. A chiral stationary phase was obtained by grafting these monomers to polysiloxane.
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