以环己烷和正十八烷为囊心,用原位聚合法合成了三聚氰胺-甲醛树脂为囊壁的相变材料纳米胶囊,在不同温度下对胶囊热处理不同的时间,采用SEM,DSC,TG-DTA和IR等测试手段对胶囊的性能进行了研究.结果表明,热处理对胶囊的表观形貌、相变性能和耐热性能有很大的影响,热处理过程中环己烷扩散出囊壁,在胶囊内形成预留膨胀空间,使胶囊的耐热温度增高.当热处理温度为160~180℃,热处理时间在30~60min时,得到的胶囊破裂较少,胶囊的相变热为150J/g,耐热温度可以达到215℃左右.
参考文献
[1] | Marty J J;Oppenheim R C;Speiser P .Nanoparticles-a new colloidal drug delivery system[J].Pharm Acta Pharm Acta Helv,1978,53(01):17-23. |
[2] | Oppenheim R C;Stewart N F;Gordon L et al.The production and evaluation of orally administered insulin nanoparticles[J].Drug Development and Industrial Pharmacy,1982,8:531-536. |
[3] | Florence A T .The oral absorption of micro- and nanoparticulates: Neither exceptional nor unusual[J].Pharmaceutical Research,1997,14:259-266. |
[4] | Mosqueira VC;Legrand P;Gulik A;Bourdon O;Gref R;Labarre D;Barratt G .Relationship between complement activation, cellular uptake and surface physicochemical aspects of novel PEG-modified nanocapsules.[J].Biomaterials,2001(22):2967-2979. |
[5] | Calvo P.;Alonso MJ.;Vilajato JL. .EFFECT OF LYSOZYME ON THE STABILITY OF POLYESTER NANOCAPSULES AND NANOPARTICLES - STABILIZATION APPROACHES[J].Biomaterials,1997(19):1305-1310. |
[6] | Aboubakar M;Puisieux F;Couvreur P;Vauthier C .Physico-chemical characterization of insulin-loaded poly(isobutylcyanoacrylate) nanocapsules obtained by interfacial polymerization.[J].International Journal of Pharmaceutics,1999(1):63-66. |
[7] | Lu Ze;Bei Jianzhong;Wang Shenguo .A method for preparation of polymeric nanocapsules without stabilizer[J].Journal of Controlled Release,1999,61:107-112. |
[8] | Cho J-S;Kwon Cho C-G .Microencapsulation of octadecane as a phase-change material by interfacial polymerization in an emulsion system[J].Colloid and Polymer Science,2002,280:260-266. |
[9] | Kim J;Cho G .Thermal storage/release durability, and tempera ture sensing properties of thermostatic fabrics treated with octadecane-coating microcapsules[J].Textile Research Journal,2003,72(12):1093-1098. |
[10] | Lee Won-Mok .Microcapsule containing phase change material and article having same[P].WO:02053370,2002. |
[11] | Yamagishi Y;Sugeno T;Ishige T.An evaluation of microencapsulated PCM for use in cold energy transportation medium[J].IEEE,1996:2077-2083. |
[12] | Bryant Y G .Melt spun fibers containing microencapsultated phase change material[Z].HTD-Vol 363/BED-Vol 44,1999. |
[13] | Mahnke H;Kreibiehl G;Weber H et al.Manufacture of resilient foams based on a melamine-formaldehyde condensate[P].US:4334971,1982. |
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