设计和制备一种适合口腔牙槽骨缺损修复的多层功能膜.利用溶液铺展法和静电纺丝法制备3层多功能膜;通过扫描电镜得到修复膜微观形貌结果,力学性能测试结果得到拉伸强度为6.5 MP a;进行模拟体液的药物释放发现释放时间可持续3 d.结果表明,3层多功能膜引入致密PCL层获得更高的机械强度,添加明胶抗菌层获得了抗菌功能.
This paper design a multifunctional alveolar bone regeneration membrane.Preparation the three-lay-ered membrane by solution spreading and electrospinning.The microstructure observation was carried out by scanning electron microscopy (SEM);the three-layered structure demonstrated higher strength (6 .5 MPa);the drug release showed sustainable 3 d time.The results testified that it is promising for use in alveolar bone re-generation.
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