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设计和制备一种适合口腔牙槽骨缺损修复的多层功能膜.利用溶液铺展法和静电纺丝法制备3层多功能膜;通过扫描电镜得到修复膜微观形貌结果,力学性能测试结果得到拉伸强度为6.5 MP a;进行模拟体液的药物释放发现释放时间可持续3 d.结果表明,3层多功能膜引入致密PCL层获得更高的机械强度,添加明胶抗菌层获得了抗菌功能.

This paper design a multifunctional alveolar bone regeneration membrane.Preparation the three-lay-ered membrane by solution spreading and electrospinning.The microstructure observation was carried out by scanning electron microscopy (SEM);the three-layered structure demonstrated higher strength (6 .5 MPa);the drug release showed sustainable 3 d time.The results testified that it is promising for use in alveolar bone re-generation.

参考文献

[1] Blanco J;Alonso A;Sanz M.Long-term results and survival rate of implants treated with guided bone regeneration: a 5-year case series prospective study.[J].Clinical oral implants research,20053(3):294-301.
[2] Geurs NC;Vassilopoulos PJ;Reddy MS.Soft tissue considerations in implant site development.[J].Oral and Maxillofacial Surgery Clinics of North America,20103(3):387-405; vi-vii.
[3] 孟维艳;周延民;储顺礼;车彦海;王林.种植体周不同骨量缺损修复的组织学研究[J].现代口腔医学杂志,2009(2):124-127.
[4] Piergiorgio Gentile;Valeria Chiono;Chiara Tonda-Turo.Polymeric membranes for guided bone regeneration[J].Biotechnology Journal: Healthcare,Nutrition,Technology,201110(10):1187-1197.
[5] Taguchi Y;Amizuka N;Nakadate M;Ohnishi H;Fujii N;Oda K;Nomura S;Maeda T.A histological evaluation for guided bone regeneration induced by a collagenous membrane[J].Biomaterials,200531(31):6158-6166.
[6] 王杏松.口腔修复膜材料在牙种植中引导骨再生中的应用分析[J].中国医药指南,2014(04):172-172,173.
[7] Bottino MC;Thomas V;Janowski GM.A novel spatially designed and functionally graded electrospun membrane for periodontal regeneration.[J].Acta biomaterialia,20111(1):216-224.
[8] Swetha, M.;Sahithi, K.;Moorthi, A.;Srinivasan, N.;Ramasamy, K.;Selvamurugan, N..Biocomposites containing natural polymers and hydroxyapatite for bone tissue engineering[J].International Journal of Biological Macromolecules: Structure, Function and Interactions,20101(1):1-4.
[9] 许岗;杨觉明;陈平.疏水复合薄膜接触角的测定[J].西安工业学院学报,2004(1):65-69.
[10] Seyed Fakhreddin Hosseini;Masoud Rezaei;Mojgan Zandi;Farhid Farahmand Ghavi.Preparation and functional properties of fish gelatin-chitosan blend edible films[J].Food Chemistry,20133/4(3/4):1490-1495.
[11] 凌智钢;唐延林;李涛;李玉鹏;杜建宾.甲硝唑、替硝唑和奥硝唑的结构与光谱[J].原子与分子物理学报,2013(4):553-558.
[12] 卢杨辉;陈永吉;罗志晓;余和东;冷卫东.e-PTFE膜联合Bio-oss骨代材料在种植手术中引导骨再生的应用研究[J].临床口腔医学杂志,2014(2):99-101.
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