通过共沉淀法制备氧化铁磁性纳米颗粒,用壳聚糖对其表面进行修饰得到样品(CS@MNPS);表征其形貌结构、尺寸、表面基团、表面电荷、磁学性质和在不同介质中的稳定性等.实验结果表明,CS@ MNPs具有典型的立方反尖晶石晶体结构;粒径为16.5nm;在生理(pH值7.4)条件下拥有较高的正电荷(10mY);呈现超顺磁性,对驰豫时间T1、T2,尤其是T2*具有很强的响应;在双蒸馏水和含10％新生牛血清的RPMI 1640培养液中具有良好的稳定性,具有作为磁共振造影剂的潜力.
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