采用先水解再键合羟乙基纤维素的方法对尼龙6膜进行改性,使膜上的可反应基团数目由10*!μmol/g膜增加至178*!μmol/g膜,并且增加了膜的亲水性,使膜基质对蛋白质的非特异性吸附大大降低.羟乙基纤维素改性膜对牛γ-球蛋白的吸附量由5.53*!mg/g膜降到0.95*!mg/g膜,对牛血清白蛋白的吸附量由1.51*!mg/g膜降到0.羟乙基纤维素改性后膜的孔径为原始膜的78%～82%.改性后的膜适宜用做亲和分离介质.
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