综述了接触透镜材料的研究进展,接触透镜从材料方面主要分为硬镜和软镜;介绍了各种透镜材料的成分、性能,并对其优缺点进行评定.聚甲基丙烯酸甲酯(PMMA)是最初的接触透镜材料,随后研制出透气性硬镜材料(RGP)以保持佩戴角膜健康.为改善佩戴舒适性,广泛研究水凝胶类软接触透镜材料,主要有聚甲基丙烯酸β-羟乙酯(HEMA)、聚乙烯吡咯烷酮(PVP)和聚乙烯醇(PVA)等材料;为提高软镜的透氧性等性能,目前研究的热点是高透氧性软接触透镜材料,主要以有机硅、有机氟等大分子单体合成水凝胶材料,以及生物改性的软镜材料.
参考文献
| [1] | Hehl EM;Beck R;Luthard K;Guthoff R;Drewelow B .Improved penetration of aminoglycosides and fluorozuinolones into the aqueous humour of patients by means of Acuvue contact lenses.[J].European journal of clinical pharmacology,1999(4):317-323. |
| [2] | Hiratani H.;Alvarez-Lorenzo C. .Timolol uptake and release by imprinted soft contact lenses made of N,N-diethylacrylamide and methacrylic acid[J].Journal of Controlled Release: Official Journal of the Controlled Release Society,2002(2):223-230. |
| [3] | 崔英德,黎新明.PVP水凝胶的应用与制备研究进展[J].化工科技,2002(02):43-47. |
| [4] | Koch MU;Kalicharan D;van der-Want-JJ .Lens epithelial cell layer formation related to hydrogel foldable intraocular lenses.[J].Journal of cataract and refractive surgery,1999(12):1637-1640. |
| [5] | 黄汉生.高氧透过性隐形眼镜[J].化工新型材料,1996(01):30-32. |
| [6] | USP Dictionary of USAN and International Drug Names[M].Rockville,M D:US Pharmacopeia,Convention Inc,2000:259. |
| [7] | Legeais J M;Werner L;Briat B et al.A new biomaterial for intraocular lens:experimental in vivo study[J].Vision Research,1995,35(01):125. |
| [8] | Mathivet T;Monflier E;Castanet Y .Easy two-step synthesis of new tris (perfluoroalkylphenyl) phosphates[J].Tetrahedron Letters,1998,39:9411-9414. |
| [9] | Sano K;Tokoro T;Imai Y .A new drug delivery system utilizing piggyback contact lenses[J].Int ContActa Lens Clinic,1996,23(06):243-248. |
| [10] | 张华.聚乙烯吡咯烷酮的合成及应用[J].化工时刊,2002(04):34-36. |
| [11] | Thomas P D;Malcolm B H.Effect of composition on properties of copolymeric N-Vinyl-2-pyrrolidone/methylmethacrylate hydrogels and organogels[J].Journal of Polymer,1990(03):513-516. |
| [12] | 王小红,马建标,何炳林.甲壳素,壳聚糖及其衍生物的应用[J].功能高分子学报,1999(02):197-202. |
| [13] | Marner K;Moller P M;Dillon M et al.Viscous carbomer eye drops in patients with dry eyes:efficacy and safety,a randomised,open,cross-over,multicentre study[J].Int ContActa Lens Clinic,1996,23(06):242-243. |
| [14] | Liu Z;Pflugfelder SC .The effects of long-term contact lens wear on corneal thickness, curvature, and surface regularity.[J].Ophthalmology,2000(1):105-111. |
| [15] | Jinkerson D L;Freeman C;Karakelle M et al.Improved high refractive index ophthalmic lens materials[P].WO 9640303,1996-12-19. |
| [16] | Keay L;Willcox M D P;Sweeney D F et al.Bacterial populations on 30-night extended wear of silicone hydrogel contact lenses[J].CLAO Journal,2001,27:30-34. |
| [17] | Fandelan D G;Hajes M;Wilians S et al.Soft contact lens[P].US 09033347,1998-03-02. |
| [18] | Chaouk H;Meijs G F .High water content porous polymer[P].WO 9735906,1997-10-02. |
| [19] | Kongsle J F;Aozak R M .Fluorin-siloxane hydrogel materials[P].US 08017056,1993-02-22. |
| [20] | Court JL iocompatibles.co.uk;Redman RP;Wang JH;Leppard SW;Obyrne VJ;Small SA;Lewis AL;Jones SA;Stratford PW .A novel phosphorylcholine-coated contact lens for extended wear use.[J].Biomaterials,2001(24):3261-3272. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%