模仿生物膜的表面结构形态,将有序的、流动的胆甾醇液晶(LC)与基质材料聚氨酯(PU)共混,在不同强度的电场条件下制成取向PU/LC复合膜,作为抗凝血生物材料.表征了不同取向条件下复合膜表面液晶畴取向性、体积、形状及其与电场强度、液晶含量的相关关系.结果表明:复合膜表面呈现出的形态特征是液晶含量、电场强度综合影响的结果;电场可以调控指状液晶畴的体积、分布,通过电场调控可获得具有适宜相分离程度和有序性的复合膜.
参考文献
| [1] | 俞耀庭.生物医用材料[M].天津:天津大学出版社,2000:224. |
| [2] | Mowery KA;Schoenfisch MH;Saavedra JE;Keefer LK;Meyerhoff ME .Preparation and characterization of hydrophobic polymeric films that are thromboresistant via nitric oxide release.[J].Biomaterials,2000(1):9-21. |
| [3] | Tanaka M;Motomura T;Kawada M;Anzai T;Kasori Y;Shiroya T;Shimura K;Onishi M;Mochizuki A .Blood compatible aspects of poly(2-methoxyethylacrylate) (PMEA)--relationship between protein adsorption and platelet adhesion on PMEA surface.[J].Biomaterials,2000(14):1471-1481. |
| [4] | Ji J.;Qiu YX.;Yu XJ.;Feng LX. .Stearyl poly(ethylene oxide) grafted surfaces for preferential adsorption of albumin Part 2. The effect of molecular mobility on protein adsorption[J].Polymer: The International Journal for the Science and Technology of Polymers,2000(10):3713-3718. |
| [5] | Montanaro L;Arciola CR;Cenni E;Ciapetti G;Savioli F;Filippini F;Barsanti LA .Cytotoxicity, blood compatibility and antimicrobial activity of two cyanoacrylate glues for surgical use.[J].Biomaterials,2001(1):59-66. |
| [6] | McClung WG;Clapper DL;Hu SP;Brash JL .Adsorption of plasminogen from human plasma to lysine-containing surfaces.[J].Journal of biomedical materials research, Part B. Applied biomaterials,2000(3):409-414. |
| [7] | Lihua Li;Mei T;Shansong M et al.Preparation and blood compatibility of potysiloxane/liquid crystal composite membranes[J].Biomaterials,2001,22:2595-2599. |
| [8] | 孙润广;王永昌.生物膜分子的液晶态构象与运动[J].原子与分子物理学报,1998:319. |
| [9] | Zhou C;Yi Z .Blood-compatibility of polyurethane/liquid crystal composite membranes.[J].Biomaterials,1999(22):2093-2099. |
| [10] | Kitzerow H S;Crooker P P .Electric field effects on the droplet structure in polymer dispersed cholesteric liquid crystals[J].Liquid Crystals,1993,13(01):31-43. |
| [11] | 任洪文,黄锡珉,凌志华.聚合物分散液晶膜中液晶分子的电场取向效应[J].液晶与显示,1998(01):33. |
| [12] | 胡国栋.聚氨酯的血液相容性评价[J].国外医学(生物医学工程分册),2002(06):271-273,284. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%