对低聚壳聚糖制备液进行了纳滤纯化研究,试验确定纳滤的最佳操作条件为35~40℃、操作压力为1.0 MPa,制备液在纳滤之前还应稀释2.5倍,间歇恒容渗滤过程的每一运行周期的最优浓缩倍数为1.5倍.在该条件运行下,制备液中的单糖和大部分二糖及一价盐离子被脱出,高活性低聚壳聚糖的纯度高达92%,料液体积浓缩接近2倍.
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