采用一步细乳液聚合法将荧光单体4-甲胺基-9-(2-烯丙基)-1,8-萘二甲酰亚胺(MANI)共价键结合进聚合物纳米粒子中.光谱特性研究证明了MANI已经成功结合进人纳米粒子中.更重要的是,因为MANI通过共价键的方式结合进聚合物纳米粒子中,可以有效避免产生染料泄漏现象.并且可以通过控制纳米粒子中MANI的含量,来获得不同荧光强度的荧光聚合物纳米粒子.这类新型荧光聚合物纳米粒子在生物医学等领域具有潜在的应用价值.
参考文献
[1] | Mason W T.Fluorescent and luminescent probes for biological activity[M].London,UK:Academic Press,1999 |
[2] | Lakowiez J R.Principles of fluorescence spectroscopy[M].New York:Springer Science,2006 |
[3] | Zhang J;Campbell RE;Ting AY;Tsien RY .Creating new fluorescent probes for cell biology.[J].Nature Reviews. Molecular cell biology,2002(12):906-918. |
[4] | Waggoner A .Fluorescent labels for proteomics and genomics[J].Current opinion in chemical biology,2006(1):62-66. |
[5] | Tan L;Li Y;Drake TJ;Moroz L;Wang KM;Li J;Munteanu A;Yang CYJ;Martinez K;Tan WH .Molecular beacons for bioanalytical applications[J].The Analyst: The Analytical Journal of the Royal Society of Chemistry: A Monthly International Publication Dealing with All Branches of Analytical Chemistry,2005(7):1002-1005. |
[6] | de Lorimier RM;Smith JJ;Dwyer MA;Looger LL;Sali KM;Paavola CD;Rizk SS;Sadigov S;Conrad DW;Loew L;Hellinga HW .Construction of a fluorescent biosensor family.[J].Protein Science: A Publication of the Protein Society,2002(11):2655-2675. |
[7] | Wang L;Tan W H .Muhicolor FRET silica nanoparticles by single wavelength excitation[J].Nano Letters,2006,6(01):84-88. |
[8] | Chen, J.;Zhang, P.;Yi, P. .Preparation of fluorescence tunable polymer nanoparticles by one-step mini-emulsion[J].Journal of Macromolecular Science. Pure and Applied Chemistry,2010(10/12):1135-1141. |
[9] | Chen J;Zeng F;Wu S Z;Chen Q M,Tong Z .A core-shell nanoparticle approach to photoreversible fluorescence modulation of a hydrophobie dye in aqueous media[J].Chemistry-a Eu ropean Journal,2008,14(16):4851-4860. |
[10] | Konstantinova T N;Meallier P;Grabchev I .The Synthesis of some 1,8-naphthalic an.hydride derivatives as dyes for polymeric materials[J].Dyes and Pigments,1993,22(03):191-198. |
[11] | Grabtchev I;Konstantinov T;Guittonneau S;Meallier P .Photochemistry of some 1.8-naphthalic anhydride derivatives[J].Dyes and Pigments,1997,35(04):361-366. |
[12] | Wei-Bing Wu;Ming-Liang Wang;Yue-Ming Sun;Wei Huang;Yi-Ping Cui;Chun-Xiang Xu .Color-tuned FRET polystyrene microspheres by single wavelength excitation[J].Optical materials,2008(12):1803-1809. |
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