采用溶胶凝胶自蔓延法制备生物凝胶玻璃粉,采用冷等静压法压制成圆片状和圆柱状,对经过烧结处理的两种生物凝胶玻璃陶瓷样品在体外、体内环境中的生物学行为进行了研究.试验结果表明:两试样均具有很好的体外生物活性和体内组织相容性,其中,硅含量较低的试样的体外生物活性优于硅含量较高的试样;而硅含量较高的试样的组织相容性较好且具有一定的骨诱导能力.试验证明:体外试验与体内试验的结果具有一定相关性,但对体内植入试验只起到一定的指导性所用.
参考文献
| [1] | 赖琛;唐绍裘.生物陶瓷材料在生物材料中的应用[J].陶瓷工程,2000(12):41. |
| [2] | 蔡玉荣,武军,周廉.生物玻璃材料研究进展[J].材料导报,2002(12):40-42. |
| [3] | Park K;Vasilos T .[J].Journal of Materials Science Letters,1997,16:985. |
| [4] | 崔福斋;冯庆玲.生物材料学[M].北京:科学出版社,1996 |
| [5] | Fernandez-Lorenzo C;Esquivias L;Barboux P et al.Sol-Gel synthesis of SiO2-P2O5 glasses[J].Journal of Non-Crystalline Solids,1994,176:189-199. |
| [6] | Rosana Z. Domingues;Arthur E. Clark;Anthony B. Brennan .A sol-gel derived bioactive fibrous mesh[J].Journal of biomedical materials research, Part B. Applied biomaterials,2001(4):468-474. |
| [7] | Greenspan DC;Zhong JP;Latorre GP .Effect of surface area to volume ratio on in vitro surface reactions of bioactiveglass particulates[J].Bioceramics,1994,7:28-33. |
| [8] | Dean Mo Liu;Quanzu Yang;Tom Troczynski;Wenjea J Tseng .Structural evolution of sol-gel-derived hydroxyapatite[J].Biomaterials,2002,23:1679. |
| [9] | J. M. Gomez-Vega;A. Hozumi;E. Saiz .Bioactive glass-mesoporous silica coatings on Ti6Al4V through enameling and triblock-copolymer-templated sol-gel processing[J].Journal of biomedical materials research, Part B. Applied biomaterials,2001(3):382-389. |
| [10] | Cai yurong;Zhou Lian;Wang Keguang.A New Chemical Process to Rapidly Synthesize Ultrafine Bioactive glass Precursor Powder[A].,2004:1041. |
| [11] | Ikarashi Y .Comparative studies by cell culture and in vivo implantation test on the toxicy of natural latex materials[J].Journal of Biomedical Materials Research,1992,26(03):339-356. |
| [12] | J Huang;L Di Silvid;M Wang et al.Evaluation of in vitro bioactivity and biocompatibility of bioglass-reinforced polyethylene composite[J].Journal of Materials Science:Materials in Medicine,1997,8:809-813. |
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