在总结近年来国内外有关磁性药物微球研究成果的基础上,对磁性药物微球的几种制备方法,即直接包埋法、乳液聚合法和沉淀法的基本原理、工艺过程及特点进行了综述.
参考文献
| [1] | 邱广亮;邱广明;石晶瑜 等.磁性靶向顺铂白蛋白微球的研究[J].广州化工,2000,28(04):103. |
| [2] | 吴传斌;魏树礼 .磁性药物微球研究进展[J].中国药学杂志,1993,28(06):330. |
| [3] | 郑幼伟,张培云.磁性药物微球靶向性治疗恶性肿瘤的研究进展[J].河南肿瘤学杂志,2003(04):309-312. |
| [4] | Gupta P K;Hung C T .Magnetically controlled targeted micro-carrier systems[J].Life Sciences,1989,44:175. |
| [5] | Widder K J;Senyei A E;Scarpelli D G .Magnetic microspheres:a model system for site special drug delivery in vivo[J].Proceedings of the Society for Experimental Biology and Medicine,1978,58(01):141. |
| [6] | Widder K;Flouret G;Senyei A .Magnetic microspheres:Synthesis of a novel parenteral drug carrier[J].Journal of Pharmaceutical Sciences,1979,68(01):79. |
| [7] | 沈海霞,陈晓耕,刘振华,林孟波,李忠琴,许小平.阿霉素磁性高分子抗癌微球的制备与表征[J].中国新医药,2004(04):15-16. |
| [8] | Senyei A E;Widder K J;Czerlinski G .Magnetic guidance of drug carrying microspheres[J].Journal of Applied Physics,1978,49(12):3758. |
| [9] | Kumar M .Nano and microparticles as controlled drug delivery devices[J].Journal of Pharmaceutical Sciences,2000,3(02):234. |
| [10] | Kumaresh S S;Tejraj M A;Anandraw R K et al.Biodegradable polymeric nanoparticles as drug delivery devices[J].Journal of Controlled Release,2001,70:1. |
| [11] | Gallo J M;Hassan E E .Receptor-mediated magnetic carriers:basis for targeting[J].Pharmaceutical Research,1988,5(05):300. |
| [12] | Torchilin V P;Papisov M I;Smirnov V N .Magnetic sephadex as a carrier for enzymeimmobilization and drug targeting[J].Journal of Biomedical Materials Research,1985,19:461. |
| [13] | Fahlvik A K;Holtz E;Schroder U et al.Magnetic starch microspheres,biodistribution and biotransformation[J].Investigative Radiology,1990,25(07):793. |
| [14] | Ibrahim A;Couvreur P;Roland M et al.New magnetic drug carrier[J].Journal de Pharmacologie,1983,35:59. |
| [15] | Gómez-Loper S A;Plaza R C;Delgado A V .Synthesis and characterization of spherical magnetite/biodegradable polymer composite particles[J].Journal of Colloid and Interface Science,2001,240:40. |
| [16] | Duguay D G .Magnetically responsive polylactic acid microspheres for targetable drug delivery[D].McGill University:Department of chemical engineering,1991. |
| [17] | Roullin VG;Deverre JR;Lemaire L;Hindre F;Venier Julienne MC;Vienet R;Benoit JP .Anti-cancer drug diffusion within living rat brain tissue: an experimental study using (3H)(6)-5-fluorouracil-loaded PLGA microspheres.[J].European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fuer Pharmazeutische Verfahrenstechnik e.V,2002(3):293-299. |
| [18] | 张凯,傅强,黄渝鸿,周德惠.磁性高分子微球的制备及表征技术[J].宇航材料工艺,2004(06):1-5. |
| [19] | 刘先桥,官月平,邢建民,马志亚,刘会洲.磁性微球的制备及在细胞分离中的应用[J].化学通报（印刷版）,2004(10):723-728. |
| [20] | Sussan G;Turaj E;Seyed M et al.Dexamethasone-loaded magnetic albumin microspheres:preparation and in vitro release[J].International Journal of Pharmaceutics,1996,130:49. |
| [21] | Widder K J;Senyei A E;Ranney D F et al.In vitro release of biologically active adriamycin by magnetically responsive albumin microspheres[J].Cancer Research,1980,40(10):3512. |
| [22] | 彭道兴.5-氟脲嘧啶磁性微球的制备及其性能的探讨[J].现代应用药学,1992(03):101. |
| [23] | 陶凯雄,陈道达,田源.抗癌药阿霉素磁性蛋白微球的制备及其细胞毒试验[J].华中科技大学学报（医学版）,1999(05):418-420. |
| [24] | 张玉,王凯平,陈东生,杨波.复方阿霉素磁性白蛋白微球的制备及含量测定[J].中国医院药学杂志,2000(01):53-55. |
| [25] | 张阳德,龚连生.磁性阿霉素白蛋白纳米粒的研制[J].中国现代医学杂志,2001(03):1-3. |
| [26] | 马建华,陈道达,田源,陶凯雄.阿霉素磁性蛋白微球的改良法制备[J].中华实验外科杂志,2002(03):272-273. |
| [27] | 王国斌,刘敬伟,陶凯雄,李剑星,田元.丝裂霉素C磁性纳米微球的制备[J].中国新药杂志,2004(12):1120-1123. |
| [28] | 林本兰,沈晓冬,崔升,施瑞华,凌亭生.磁性纳米粒阿霉素微球制备的初探[J].中国医院药学杂志,2005(05):424-426. |
| [29] | Chuan-Bin Wu,Shu-Li wei,WEI Lu,Su-Mei He,Wen-Wei Gao,Tian-Li Wang,Xuan Li,Jing-Xia Xie.Studies on Adriamycin Magnetic Gelatin Microspheres[J].中国药学（英文版）,1995(01):1. |
| [30] | Longo W;Iwata H;Lindheimer T et al.preparation of hydrophilic albumin using polymeric dispersing agents[J].Journal of Pharmaceutical Sciences,1982,71:1323. |
| [31] | Gupta P K;Hung C T;Lam F C .Albumin microspheres Ⅲ:synthesis and characterization of microspheres containing adriamycin magnetic[J].International Journal of Pharmaceutics,1988,43(01):167. |
| [32] | 邱广亮,李咏兰,丁炜.磁性导向柔红霉素白蛋白微球的研究[J].精细化工,2001(03):141-143,147. |
| [33] | 刘利萍,李苹,吴泽志,蔡绍皙.5-Fu壳聚糖/丝素复合磁微球的制备及体外性质研究[J].中国药学杂志,2003(10):774-777. |
| [34] | 刘利萍,李苹,吴泽志,蔡绍皙.肺靶向利福平壳聚糖磁微球的构建[J].化学世界,2003(04):200-202,190. |
| [35] | 张皖清,毛天球,孙玉鹏,何远辉,王文学.磁导向甲氨蝶呤缓释药物的研制及含量测定[J].实用口腔医学杂志,2000(01):61-64. |
| [36] | 王平康;袁青禄;刘歧山 等.磁性抗癌药物载体的研制[J].中国医院药学杂志,1990,10(01):2. |
| [37] | 郑根建;周嘉秀;李德伦 等.平阳霉素磁控缓释微球的制备[J].华西口腔医学杂志,1996,14(03):220. |
| [38] | Fujimoto S;Miyazaki M;Endoh F et al.Effects of intraaterially infused biodegradable microspheres containing Mitomycin C[J].Cancer,1985,55(09):522. |
| [39] | Tanaka B;Takino S;Utsumi I .A new oral gelatinized sustained-release dosage form[J].Journal of Pharmaceutical Sciences,1963,5(06):66439. |
| [40] | 张胜,吴汉江,凌天牖.平阳霉素磁性微球的制备及特性检测[J].湖南医科大学学报,2003(02):191-193. |
| [41] | 王彦卿,张朝平.诺氟沙星明胶磁性微球的研制及表征[J].无机材料学报,2005(01):77-82. |
| [42] | 吴远,叶红军,王家马龙,黄杰,李剑星,任恕,胡斌,范昌烈,卓仁禧.含肿瘤坏死因子聚碳酸酯磁性微球的制备及靶向治疗原发性肝癌的实验研究[J].胃肠病学和肝病学杂志,2001(01):33-35,38. |
| [43] | 吴远;王家龙 .丝列霉素-聚碳酸酯微球的制备及靶向治疗原发性肝癌的实验研究[J].华夏医学,2001,14(01):1. |
| [44] | 高虹,王吉耀,邓勇辉,张伟,沈锡中.载阿克拉霉素磁性聚氰基丙烯酸正丁酯纳米微球的制备及抗肿瘤效应[J].中华消化杂志,2004(05):259-262. |
| [45] | Sommerfeld P;Sabel B A;Schroeder U .Long-term stability of PBCA nanoparticle suspensions[J].Journal of Microencapsulation,2000,17:69. |
| [46] | Watasirichaikul S;Davies N M;Rades R et al.Preparation of biodegradable insulin nanocapsules from biocompatible microemulsions[J].Pharmaceutical Research,2000,17:684. |
| [47] | 吕慧丹,刘峥,刘勇平.磁性高分子微球的制备及生物医学应用[J].化工新型材料,2004(03):10-13,9. |
| [48] | 刘利萍,吴泽志,李苹,傅遍红.天然高分子磁微球作为靶向制剂的研究进展[J].药物生物技术,2004(01):68-70. |
| [49] | M. L. Hans;A. M. Lowman .Biodegradable nanoparticles for drug delivery and targeting[J].Current opinion in solid state & materials science,2002(4):319-327. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%