利用液体石蜡作分散介质,戊二醛作交联剂,制备出粒径为300～500μm,孔径50～70μm,孔隙率86%的大孔壳聚糖微载体,并以乳糖对微载体进行了糖基化修饰,在优化条件下其接糖量可达到42.6mg/g载体.用原代大鼠肝细胞进行材料的细胞相容性研究,结果显示乳糖修饰的壳聚糖大孔微载体具有良好的细胞相容性.
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