采用化学气相沉积聚合(CVDP)的方法制备了聚对亚苯基二亚甲基(PPX)涂层,再通过发烟硫酸的化学表面改性成功地在PPX的芳香环上引入磺酸基团,可作为进一步功能化的反应基团.与PPX相比,表面磺化改性PPX(PPX-SO3Na)的接触角变小,亲水性增加,更有利于作为生物医用材料.采用原子力显微镜(AFM)测定PPX和磺化PPX的表面形貌,结果表明,表面磺化改性后的PPX变得更光滑,更有利于作抗凝血涂层材料.Fenton试剂测得PPX-SO3Na的抗化学氧化时间略低于PPX,但由于膜的主链主要是由苯环连接而成的,相对其它常用聚合物来说依然具有较好的抗化学氧化性能.
参考文献
| [1] | Gorham W F .[J].Journal of Polymer Science Part A:Polymer Chemistry,1966,4:3027. |
| [2] | 浦鸿汀,孙霞容.聚对苯撑二甲基系列涂层的制备及其应用进展[J].高分子通报,2004(02):78-84. |
| [3] | 浦鸿汀,王永星.聚酰亚胺气相沉积聚合的研究进展[J].高分子材料科学与工程,2005(05):5-9. |
| [4] | Lahann J.;Hocker H.;Klee D. .Chemical vapour deposition polymerization of substituted [2.2]paracyclophanes[J].Macromolecular rapid communications: Publishing the newsletters of the European Polymer Federation,1998(9):441-444. |
| [5] | Lahann J;Hcker H;Langer R .[J].Angewandte Chemie International Edition,2001,40:726. |
| [6] | Lahann J;Klee D;Pluester W et al.[J].Biomaterials,2001,22:17. |
| [7] | Lahann J;Choi IS;Lee J;Jenson KF;Langer R .A new method toward microengineered surfaces based on reactive coating[J].Angewandte Chemie International Edition,2001(17):3166-3169. |
| [8] | Lahann J.;Balcells M.;Rodon T.;Lee J.;Choi IS.;Jensen KF.;Langer R. .Reactive polymer coatings: A platform for patterning proteins and mammalian cells onto a broad range of materials[J].Langmuir: The ACS Journal of Surfaces and Colloids,2002(9):3632-3638. |
| [9] | Herrera-Alonso M;McCarthy TJ .Chemical surface modification of poly(p-xylylene) thin films[J].Langmuir: The ACS Journal of Surfaces and Colloids,2004(21):9184-9189. |
| [10] | 顾汉卿;徐国风.生物医学材料学[M].天津:天津科技翻译出版公司,1993 |
| [11] | Han DK.;Park KD.;Kim YH.;Cho HI.;Min BG.;Lee NY. .HEPARIN-LIKE ANTICOAGULANT ACTIVITY OF SULPHONATED POLY(ETHYLENE OXIDE) AND SULPHONATED POLY(ETHYLENE OXIDE)-GRAFTED POLYURETHANE[J].Biomaterials,1995(6):467-471. |
| [12] | 浦鸿汀,孙霞容.CVD聚合制备聚（羟甲基对亚苯基二亚甲基）及其性能的研究[J].功能材料,2006(01):109-112,116. |
| [13] | Miyatake K.;Asano N.;Watanabe M. .Synthesis and properties of novel sulfonated polyimides containing 1,5-naphthylene moieties[J].Journal of Polymer Science, Part A. Polymer Chemistry,2003(24):3901-3907. |
| [14] | Wang XH.;Li DP.;Wang WJ.;Feng QL.;Cui FZ.;Xu YX.;Song XH. .Covalent immobilization of chitosan and heparin on PLGA surface[J].International Journal of Biological Macromolecules: Structure, Function and Interactions,2003(1/3):95-100. |
| [15] | Zhua A P;Zhang M;Wua J et al.[J].Biomaterials,2002,23:4657. |
| [16] | 愈耀庭;张兴栋.生物医用材料[M].天津:天津大学出版社,2000 |
| [17] | 浦鸿汀;侯继斅;杨正龙.[J].同济大学学报(自然科学版) |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%