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大量的细胞生物学研究显示,辐射诱发旁效应的传输信号包括活性氧自由基(ROS)、一氧化氮自由基(NO)以及一些细胞因子.近年来,越来越多的文献报道关于体内旁效应特征的研究,并已经证实在生物体内辐射诱导的旁效应不仅能发生在相邻组织,还可发生在远源器官.这些体内旁效应包括DNA损伤、表观遗传学改变、miRNA及基因表达改变、细胞增殖和凋亡等.为了总结和分析辐射诱发体内旁效应的特征,本文综述了辐射诱发体内旁效应的特点,包括其与性别、传播途径、辐射品质的关系以及相关机制的研究.

参考文献

[1] Sothersill C,Seymour C.Radiat Res,2001,155(6):759.
[2] Ballarini F,Biaggi M,Ottolenghi A,et al.Mutat Res,2002,501(1-2):1.
[3] Prise K M,O'Sullivan J M.Nat Rev Cancer,2009,9(5):351.
[4] Nagasawa H,Little J B.Cancer Res,1992,52(22):6394.
[5] Mothersill C,Seymour C B.Int J Radiat Biol,1997,71(4):421.
[6] Lehnert B E,Goodwin E H.Cancer Res,1997,57:2164.
[7] Prise K M,Belyakov O V,Folkard M,et al.Int J Radiat Biol,1998,74(6):793.
[8] Azzam E I,de Toledo S M,Gooding T,et al.Radiat Res,1998,150:497.
[9] Mothersill C,Seymour C.Radiat Res,2001,155(6):759.
[10] Little J B.Health Phys,2006,91(5):416.
[11] Rzeszowska-Wolny J,Herok R,Widel M,et al.DNA Repair,2009,8(6):732.
[12] Belyakov O V,Mitchell S A,Parikh D,et al.PNAS,2005,102(40):14203.
[13] Kovachuk O,Zemp F J,Filkowski J,et al.Carcinogenesis,2010,doi:10.109/carcin/bgq119.
[14] Chai Y F,Hei T K.Acta Med Nagasaki,2009,53(supl):65.
[15] Tubiana M.Radiother Oncol,2009,91(1):4.
[16] Suit H,Goldberg S,Niemeierko A,et al.Radiat Res,2007,167(1):12.
[17] Khan M A,Van Dyk J,Yeung I W,et al.Radiother Oncol,2003,66(1):95.
[18] Khan M A,Hill R P,Van Dyk J.Int J Radiat Oncol Biol Phys,1998,40(2):467.
[19] Koturbash I,Rugo R E,Hendricks C A,et al.Oncogene,2006,25(31):4267.
[20] Mancuso M,Pasquali E,Leonardi S,etal.PNAS,2008,105(34):12445.
[21] Koturbash I,Boyko A,Rodriguez-Juarez R,et al.Carcinogenesis,2007,28(8):1831.
[22] Tamminga J,Koturbash I,Baker M,et al.Cell Cycle,2008,7(9):1238.
[23] Ilnytskyy Y,Koturbash I,Kovalchuk O.Environ Mol Mutagen,2009,50(2):105.
[24] Ilnytskyy Y,Koturbash I,Kovalchuk O.Environ Mol Mutagen,2009,50(2):105.
[25] Watson G E,Lorimore S A,Macdonald D A,et al.Cancer Res,2000,60(20):5608.
[26] Lorimore S A,McIlrath J M,Coates P J,et al.Cancer Res,2005,65(13):5668.
[27] Pasquinelli A E,Reinhart B J,Slack F,et al.Int J Radiat Biol,2005,81(2):157.
[28] Raiche J,Rodriguez-Juarez R,Pogribny I O,et al.Biochem Biophys Res Commun,2004,325(1):39.
[29] Pogribny I,Raiche J,Slovack M,etal.Biochem Biophys Res Commun,2004,320(4):1253.
[30] Koturbash I,Kutanzi K,Hendrickson K,et al.Mutation Research,2008,642(1-2):28.
[31] Koturbash I,Zemp F J,Kutanzi K,et al.Cell Cycle,2008,7(11):1658.
[32] Azzam E I,de Toledo S M,Little J B.Proc Natl Acad Sci,2001,98(2):473.
[33] Zhou H,Randers-Pehrson G,Waldren C A,et al.Proc Natl Acad Sci,2000,97(5):2099.
[34] Lyng F M,Seymour C B,Mothersill C.Radiat Res,2002,157(4):365.
[35] Cai Yujia,Zhang Hong.Nuclear Physics Review,2009,26 (3):253(in Chinese).(蔡宇伽,张红.原子核物理评论,2009,26(3):253.)
[36] Narayanan P K,Goodwin E H,Lehnert B E.Cancer Res,1997,57(18):3963.
[37] Shao C,Folkard M,Michael B D,et al.Int J Cancer,2005,116(1):45.
[38] Luce A,Courtin A,Levalois C,et al.Carcinogenesis,2009,30(3):432.
[39] Tartier L,Gilchrist L,Burdak-Rothkamm S,et al.Cancer Res,2007,67(12):5872.
[40] Langan A R,Khan M A,Yeung I W,et al.Radiother Oncol,2006,79(2):231.
[41] Calveley V L,Khan M A,Yeung I W,etal.Int J Radiat Biol,2005,81(12):887.
[42] Konopacka M,Rzeszowska-Wolny J.Mutat Res,2006,593(1-2):32.
[43] Mackonis E C,Suchowerska N,Zhang M,et al.Phys Med Biol,2007,52(18):5469.
[44] Xue L Y,Butler N J,Makrigiorgos G M,et al.Proc Natl Acad Sci,2002,99(21):13765.
[45] Kishikawa H,Wang H,Adelstein S J,et al.Radiation Res,2006,165(6):688.
[46] Mairs R J,Fullerton N E,Zalutsky M R,et al.Dose Response,2007,5(3):204.
[47] Koturbash I,Loree J,Kutanzi K,et al.Int J Radiat Oncol Biol Phys,2008,70(2):554.
[48] Ye Fei,Li Qiang.Nuclear Physics Review,2010,27(3):309(in Chinese).(叶飞,李强.原子核物理评论,2010,27(3):309.)
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