合成了含有3,5-二甲基和3,5-二氯取代基团的混合型淀粉(苯基氨基甲酸酯)衍生物(CSP-2),并作为手性体分离材料涂敷在氨丙基化多孔硅胶表面,制得新型高效液相色谱(HPLC)用手性固定相;通过1H核磁共振(1H NMR)和红外光谱(IR)表征衍生物结构;以正己烷-异丙醇(9∶1,v/v)为流动相,对多种手性对映体进行了拆分;结果表明,CSP-2综合了单一取代基团淀粉(苯基氨基甲酸酯)衍生物的手性拆分性能,具有优越的手性分离能力,同时固定相的稳定性大大增强.
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