用不同质量分数的1-乙酸乙酯基-3-甲基咪唑四氟硼酸盐([AOEMIM] [BF4])与聚乳酸(PLA)熔融共混,制得[AOEMIM][BF4]/PLA共混物.通过分析共混前后PLA数均相对分子质量(Mn)的变化及共混物在PBS缓冲液中的质量损失率、黏均相对分子质量和溶液pH值的变化,研究了[AOEMIM] [BF4]对PLA熔融加工稳定性的影响及共混物的降解性能;考察了共混物降解液对小鼠的急性毒性.结果显示,PLA经过熔融加工后,其(M)n降低了16.7％,[AOEMIM] [BF4]的加入可使(M)n的变化减小,对加工过程具有稳定作用;在降解初期,共混物的黏均相对分子质量迅速减小,降解液的pH值由7.4下降到3.0;共混物的降解随[AOEMIM][BF4]添加量的增加而加速;其降解液对小鼠无明显毒性.
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