以CaO稳定的ZrO2为原料,与适量SiO2在1400℃下反应.制得CazSiO4不同含量(质量分数:20%、40%、60%)的ZrO2改性CaO-SiO2复合粉体,并采用大气等离子体喷涂技术制备涂层.利用X射线衍射(XRD)、电子探针(ETMA)及能量色散谱(EDS)对涂层相组成和形貌进行表征.涂层的体外生物活性和稳定性以模拟体液(SBF)和Tris-HCl缓冲溶液浸泡实验进行评价.结果表明:ZrO2改性CaO-SiO2基复合涂层在SBF中浸泡后,表面形成磷灰石能力与Ca2SiO4含量有关,Ca2SiO4含量低于40%的涂层表面难以形成磷灰石;改性涂层在Tris-HCl缓冲溶液中的降解率远小于纯Ca2SiO4涂层,其降解率随Ca2SiO4含量增加而增加.通过优化涂层各组分含量,可望获得生物活性好而又抗生理体液侵蚀的长效稳定涂层.
参考文献
| [1] | Yang Y Z,Tian J M,Chen Z Q,et al.Preparation of graded porous titanium coatings on titanium implant materials by plasma spraying[J].J Biomed Mater Res,2000,52(2):333-337. |
| [2] | Anselme K,Linez P,Bigeretle M,et al.Therelative influence of the topography and chemistry of TiAI6V4 surfaces on osteoblastic cell behaviour[J].Biomaterials,2000,21(15):1567-1577. |
| [3] | Nishiguchi S,Kato H,Neo M,et al.Alkali and heat-treated porous titanium for orthopedic implants[J].J Biomed Mater Res,2001,54(2):198-208. |
| [4] | Suchanck W,Yoshimura M.Processing and properties of hydroxyapatite based biomaterials for use as hardtissue replacement implants[J].J Mater Res,1998,13(1):94-117. |
| [5] | Khor K A,Gu Y W,Pan D,Cheang P.Microstrueture and mechanical properties of plasma sprayed HA/YSZ/Ti-6Al-4V composite coatings[J].Biomaterials,2004,25(18):4009-4017. |
| [6] | Liu Xuanyong,Morra Marco,Carpi Angelo,Li Bao'e.Bioactive calciumsilicateceramicsandcoatings[J].Biomedicine ＆ Pharmacotherapy,2008,62(8):526-529. |
| [7] | Xue W,Liu X,Zheng X,Ding X.In vivo evaluation of plasmasprayed wollastonite coating[J].Biomaterials,2005,26(17):3455-3460. |
| [8] | Xue Weichang,Liu Xuanyong,Zheng Xuebin,Ding Chuanxian.Plasma-sprayer diopside coatings for biomedical applications[J].Surface ＆ Coatings Technology,2004,185(2/3):340-345. |
| [9] | De Aza P N,Fernandez-Pradas J M,Serra P.In vitro bioactivity of laser ablation pseudowollastonite coating[J].Biomaterials,2004,25(11):1983-1990. |
| [10] | Balamurugan A,Balossier G,Kannan S,et al.Electrochemical and structural characterization of zirconia reinforced hydroxyapatite bioceramic sol-gel coatings on surgical grade 316L SS for biomedical applications[J].Ceramics International,2007,33(4):605-614. |
| [11] | 张敏,汪宏斌,全仁夫,吴晓春.羟基磷灰石-二氧化锆生物复合材料的制备及其生物相容性[J].复合材料学报,2006,23(2):115-122.Zhang Min,Wang Hongbin,Quan Renfu,Wu Xiaochun.Preparation and biocompatibility of hydroxylapatite-zirconia biocomposite[J].Acta Materiae Compositae Sinica,2006,23(2):115-122. |
| [12] | 全仁夫,杨迪生,吴晓春,汪宏斌,李伟,苗旭东.二氧化锆梯度复合羟基磷灰石生物材料的制备及其生物相容性[J].复合材料学报,2006,23(3):114-122.Quan Renfu,Yang Disheng,Wu Xiaochun,Wang Hongbin,Li Wei,Miao Xudong.Preparation and biocompatibility of graded zirconia-hydroxyapatite composite ceramic[J].Acta Materiae Compositae Sinica,2006,23(3):114-122. |
| [13] | Xie Youtao,Liu Xuanyong,Zheng Xuebin,Ding Chuanxian,Chu Paul K.Improved stability of plasma-sprayed dicalcium silicate/zirconia composite coating[J].Thin Solid Films,2006,515(3):1214-1218. |
| [14] | Colin S,Dupre B,Gleitzer C.Decalcification of stabilized zirconia by silica and some other oxides[J].Journal of European Ceramic Society,1992,9(5):389-395. |
| [15] | Kokubo Tadashi,Takadama Hiroaki.How useful is SBF in predicting in vivo bone bioaetivity?[J].Biomaterials,2006,27(15):2907-2915. |
| [16] | Wang Guocheng,LiuXuanyong,DingChuanxian.Phase composition and invitro bioactivity of plasma sprayed calcia stabilized zirconia coatings[J].Surface & Coatings Technology,2008,202(24):5824-5831. |
| [17] | 俞耀庭.生物医用材料[M].天津:天津大学出版社,2000:150-152. |
| [18] | Liu Xuanyong,Tao Shunyan,Ding Chuanxian.Bioactivity of plasma sprayed dicalcium silicate coatings[J].Biomaterials,2002,23(3):963-968. |
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