采用脉冲激光方法制备了sp3/sp2不同比率的四面体非晶碳薄膜.利用拉曼光谱、紫外可见光谱等材料表征方法, 研究了脉冲激光能量对四面体非晶碳薄膜的微结构及血液相容性的影响.结果表明:脉冲激光能量显著影响四面体非晶碳薄膜中sp3/sp2的比率,调控单脉冲激光能量范围为150~250mJ,可使薄膜的光学带隙从1.41~2.44eV发生变化.血小板粘附实验和动态凝血实验表明制得的薄膜具有优良的血液相容性.分析了四面体非晶碳薄膜的抗凝血机理.
参考文献
[1] | Jones M.I.;Mccoll I.R. .Protein adsorption and platelet attachment and activation, on TiN, TiC, and DLC coatings on titanium for cardiovascular applications[J].Journal of biomedical materials research, Part B. Applied biomaterials,2000(2):413-421. |
[2] | Cui F Z;Li D J .[J].Surface and Coatings Technology,2000,131(01):481-487. |
[3] | Yu L J;Wang X;Wang X H et al.[J].Surface and Coatings Technology,2000,128:484-488. |
[4] | Chu PK.;Chen JY.;Wang LP.;Huang N. .Plasma-surface modification of biomaterials [Review][J].Materials Science & Engineering, R. Reports: A Review Journal,2002(5/6):143-206. |
[5] | LaVan DA;Padera RF;Friedmann TA;Sullivan JP;Langer R;Kohane DS .In vivo evaluation of tetrahedral amorphous carbon.[J].Biomaterials,2005(5):465-473. |
[6] | Loir A S;Garrelie F;Donnet C et al.[J].Applied Surface Science,2005,247(01):225-231. |
[7] | 郑欲芬;李仲荣.近代物理实验[M].广州:中山大学出版社,1989:82. |
[8] | Liu Yi;Li Zheyi;He Zhenhui et al.[J].Surface and Coatings Technology,2007,201:6851-6856. |
[9] | Lifshitz Y;Kasi S R;Rabalais J W et al.[J].Physical Review B:Condensed Matter,1990,15:10468-10480. |
[10] | Asano A;Stutzmann M .[J].Journal of Non-Crystalline Solids,1991,138:623-627. |
[11] | Baurschmidt P;Schaldach M .[J].Medical and Biological Engineering and Computing,1980,18:496-501. |
[12] | Chen JY;Leng YX;Tian XB;Wang LP;Huang N;Chu PK;Yang P .Antithrombogenic investigation of surface energy and optical bandgap and hemocompatibility mechanism of Ti(Ta(+5))O2 thin films.[J].Biomaterials,2002(12):2545-2552. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分:
-
10%
-
20%
-
30%
-
40%
-
50%