恶性肿瘤是一种严重威胁人类健康的常见病和多发病,是引起死亡的主要原因之一.近年来,抗肿瘤药物的靶向性研究越来越受到人们的重视.发展抗肿瘤药物的新型靶向载体,增加药物靶向性,提高生物利用度,降低毒副作用,是目前备受关注的课题.根据近年来文献,综述了一些新型的抗肿瘤药物载体,包括靶向的脂质体载药系统、纳米粒载药系统、微粒载药系统、胶束载药系统等,并分别总结了其颗粒大小、载药类型、载药模式及治疗效果等,为肿瘤的靶向给药研究提供思路.
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