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  4. NIPA系温敏凝胶结构改性及性能研究进展

材料导报, 2008, 22(7): 35-43.

NIPA系温敏凝胶结构改性及性能研究进展

侯长军 1, , 周雪松 2, , 霍丹群 3, , 杨桔 4,

1.重庆大学生物工程学院光电技术及系统教育部莺点实验室,重庆,400044

2.重庆大学化学化工学院,重庆,400044

3.重庆大学生物工程学院光电技术及系统教育部莺点实验室,重庆,400044

4.重庆大学生物工程学院,重庆,400044

基金项目:   国家高技术研究发展计划(863计划)(2006AA042349)   重庆市自然科学基金(2006BB7005)  

关键词： 温敏凝胶 , N-异丙基丙烯酰胺 , 结构改性 , 温敏性能

Development of Structural Modification and Performance Research of NIPA Series Thermosensitive Hydrogels

N-异丙基丙烯酰胺(NIPA)同时具有亲水性的酰胺基和疏水性的异丙基,使其系列聚合物具有优良的温敏智能特性和记忆效应,目前已广泛应用于药物缓释、物料分离、免疫分析、酶的固定等领域.聚合类型、多孔结构、尺寸大小、溶剂种类、工艺条件等因素对凝胶的温敏性能影响极大,为了改善凝胶性能,近年来,研究者们在这几个方面做了大量研究工作.对NIPA系温敏凝胶结构改性及温敏性能的研究进展进行了全面综述,介绍了相关机理并提出未来的发展方向.

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