在空气和氮气气氛中,对未交联的明胶微球(GMs)和戊二醛交联明胶微球(CGMs)进行了受热转变研究,并利用250 ℃热处理的明胶球制备出具有多孔内核的明胶基结构.经过热重分析(TGA)、差示扫描量热法(DSC)、扫描电子显微镜(SEM)和付里叶变换红外光谱(FTIR)等分析测试表明:戊二醛交联明胶微球300 ℃后热失重略大于未交联明胶微球,两者的熔化温度Tm都为228 ℃;在空气中250 ℃热处理7 h的未交联明胶微球经过稀硫酸处理后可以得到多孔内核结构,多孔内核含碳、氧元素,外壳以碳元素为主;105 ℃和190 ℃热处理的明胶球化学成分基本相同,250 ℃热处理使明胶分子中的酰胺键减少、并发生三级结构的转变.
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