根据近10年来有序介孔材料用于药物传递系统的研究报道,综述了几种新型介孔材料的合成方法,讨论分析了药物传递系统中孔径、孔道长度、形貌和功能基团修饰等影响因素,着重阐述和评价了影响有序介孔材料结构特征的合成工艺条件,以及这些有序介孔材料潜在的药学应用价值和急需解决的问题,旨在为新型有序介孔材料在药物传递系统中的应用提供参考.
参考文献
| [1] | Yang Q;Wang S H;Fan P W et al.pH-Responsive car-rier system based on carboxylic acid modified mesoporous silica and polyelectrolyte for drug delivery[J].Chemistry of Materials,2005,17:5999. |
| [2] | Beck J S;Vartli J C;Roth W J .A new family of mesoporous molecular sieves prepared with liquid crystal templates[J].Journal of the American Chemical Society,1992,114:10834. |
| [3] | Zhao DY.;Feng JL.;Chmelka BF.;Stucky GD.;Huo QS. .Nonionic triblock and star diblock copolymer and oligomeric surfactant syntheses of highly ordered, hydrothermally stable, mesoporous silica structures[J].Journal of the American Chemical Society,1998(24):6024-6036. |
| [4] | Wang, XF;Tian, Y;Song, GS;Zang, LQ .Synthesis and characterization of bimodal rod-like mesoporous carbons from raffinose by SBA-15 templates[J].Journal of Materials Science,2010(11):2958-2966. |
| [5] | Ryoo R;Joo S H;Jun S .Synthesis of highly ordered carbon molecular sieves via template-mediated structural transformation[J].Journal of the American Chemical Society,1999,103,37:7743. |
| [6] | 赵岚 .介孔材料的合成及高分辨点子显微镜表征[D].长春:吉林大学,2005. |
| [7] | 桂建舟,杜建亮,刘丹,宋丽娟,张晓彤,孙兆林.Au-SBA-15介孔分子筛的合成及其催化性能研究[J].工业催化,2006(05):56-60. |
| [8] | 刘秀芹,张云艳,常勇刚,徐承天,陈邦林.介孔SiO2表面的氨基修饰及吸附性能研究[J].化学世界,2009(02):70-73. |
| [9] | 王全义,李丹东,齐越,曹祖宾,刘中民.具有二次介孔分子筛材料的制备和应用[J].工业催化,2007(07):10-16. |
| [10] | 张浩然,李斌,雷炳富,李文连.共价嫁接钌（Ⅱ）配合物SBA-15介孔分子筛的光学氧传感行为[J].高等学校化学学报,2007(10):1920-1924. |
| [11] | Tian B S;Yang C .Temperature-responsive nanocomposites based on mesoporous SBA-15 silica and PNIPAAm:Synthesis and characterization[J].Journal of Physical Chemistry C,2009,113:4925. |
| [12] | Huang S S;Fan Y;Lin J et al.Magnetic mesoporous silica spheres for drug targeting and controlled release[J].Journal of Physical Chemistry C,2009,113:1775. |
| [13] | 邢伟,禚淑萍,司维江,袁勋.磁性有序介孔炭的制备及药物吸附行为研究[J].化学学报,2009(08):761-766. |
| [14] | Li Y;Zhao C F;VanSanten R A et al.Surface functiona-lization of SBA-15-ordered mesoporous silicas:Oxidation of benzenetophenolbynitrousoxide[J].Journal of Catalysis,2008,255:190. |
| [15] | Qisheng Huo;David I. Margolese;Galen D. Stucky .Surfactant Control of Phases in the Synthesis of Mesoporous Silica-Based Materials[J].Chemistry of Materials,1996(5):1147-1160. |
| [16] | Kim, TW;Kleitz, F;Paul, B;Ryoo, R .MCM-48-like large mesoporous silicas with tailored pore structure: Facile synthesis domain in a ternary triblock copolymer-butanol-water system[J].Journal of the American Chemical Society,2005(20):7601-7610. |
| [17] | 郁挺 .有序多孔材料的控制合成及其结构解析[D].复旦大学,2007. |
| [18] | Deng YH;Yu T;Wan Y;Shi YF;Meng Y;Gu D;Zhang LJ;Huang Y;Liu C;Wu XJ .Ordered mesoporous silicas and carbons with large accessible pores templated from amphiphilic diblock copolymer poly(ethylene oxide)-b-polystyrene[J].Journal of the American Chemical Society,2007(6):1690-1697. |
| [19] | Vallet-Regi M;Ramila A;delReal R P et al.A new pro-perty of MCM-41:Drug delivery system[J].Chemistry of Materials,2001,13:308. |
| [20] | Lopez T;Ortiz E .Cortisol controlled release by mesoporous silica[J].Nanomedicine:Nanotechnology Biology Medicine,2009,5:170. |
| [21] | Mellaerts R;Mols R;Jammaer JA;Aerts CA;Annaert P;Van-Humbeeck J;Van-den-Mooter G;Augustijns P;Martens JA .Increasing the oral bioavailability of the poorly water soluble drug itraconazole with ordered mesoporous silica.[J].European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fuer Pharmazeutische Verfahrenstechnik e.V,2008(1):223-230. |
| [22] | 曹渊,白英豪,夏之宁,徐彦芹.硅基介孔材料在药物缓控释中的应用[J].中国药学杂志,2009(07):481-484. |
| [23] | Fujiwara M;Yamamoto F et al.Adsorption of duplex DNA on mesoporous silicas:Possibility of inclusion of DNA into their mesopores[J].An Chem,2005,77:8138. |
| [24] | Balas F;Manzano M;Colilla M .L-Trp adsorption into silica mesoporous materials to promote bone formation.[J].Acta biomaterialia,2008(3):514-522. |
| [25] | Ruiz-Hernandez E;Lopez-Noriega A;Arcos D et al.Aerosol-assisted synthesis of magnetic mesoporous silica spheres for drug targeting[J].Chemistry of Materials,2007,19:3455. |
| [26] | Yang P;Quan Z;Lu L;Huang S;Lin J .Luminescence functionalization of mesoporous silica with different morphologies and applications as drug delivery systems.[J].Biomaterials,2008(6):692-702. |
| [27] | Horcajada P;Ramila A;Perez-Pariente J .Influence of pore size of MCM-41 matrices on drug delivery rate[J].Microporous and Mesoporous Materials,2004,68:105. |
| [28] | Qu, FY;Zhu, GS;Huang, SY;Li, SG;Sun, JY;Zhang, DL;Qiu, SL .Controlled release of Captopril by regulating the pore size and morphology of ordered mesoporous silica[J].Microporous and Mesoporous Materials,2006(1/3):1-9. |
| [29] | Salonen J;Lehto V P .Fabrication and chemical surface modification of mesoporous silicon for biomedical applications[J].Chemical Engineering Journal,2008,137:162. |
| [30] | Brian G. Trewyn;Jennifer A. Nieweg;Yannan Zhao .Biocompatible mesoporous silica nanoparticles with different morphologies for animal cell membrane penetration[J].Chemical engineering journal,2008(1):23-29. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%