Surface Coating of NiTi Shape Memory Alloys with Calcium Phosphates by Dip-coating or Plasma-spraying-biological Characterization Examined by in vitro Testing Methods

武汉理工大学学报-材料科学版(英文版), 2005, 20(z1): 7-9.

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1.Department of Surgery,BG Trauma Center Bergmannsheil,University Hospital,Buerkle-de-la-Camp-Platz 1,D-44789 Bochum,Germany

2.Department for Surgical Research,BG Trauma Center Bergmannsheil,Ruhr-University Bochum,Buerkle-de-la-Camp-Platz 1,D-44789 Bochum,Germany

3.Institute for Inorganic Chemistry,University of Duisburg-Essen,Universitaetsstr. 5-7,D-45117 Essen,Germany

4.Institute for Inorganic Chemistry,University of Duisburg-Essen,Universitaetsstr. 5-7,D-45117 Essen,Germany

5.Department of Surgery,BG Trauma Center Bergmannsheil,University Hospital,Buerkle-de-la-Camp-Platz 1,D-44789 Bochum,Germany

6.Department for Surgical Research,BG Trauma Center Bergmannsheil,Ruhr-University Bochum,Buerkle-de-la-Camp-Platz 1,D-44789 Bochum,Germany

基金项目: DFG (Deutsche Forschungsgemeinschaft) through(SFB459)

Surface Coating of NiTi Shape Memory Alloys with Calcium Phosphates by Dip-coating or Plasma-spraying-biological Characterization Examined by in vitro Testing Methods

Keywords： shape memory alloys

The influence of different surface coatings of NiTi shape memory alloys was examined using in vitro testing methods. Plates of superelastic nickel-titanium shape memory alloy (NiTi) were coated with calcium phosphates (hydroxyapatite) by high-temperature plasma-spraying or by dip-coating. The biocompatibility was tested in vitro by cultivation of isolated human granulocytes and whole blood cells. As substrates, pure NiTi,plasma-spray-coated NiTi and dip-coated NiTi were used. Isolated granulocytes showed an increased adhesion to both calcium phosphate-coated NiTi samples. Compared to non-coated NiTi or dip-coated NiTi, the number of dead granulocytes adherent to plasma-sprayed surfaces was significantly increased (p ＜ 0.01). Whether the differences in apoptosis of granulocytes on dip-coated vs plasma-sprayed coatings observed are due to differences in material surface morphologies bas to be analyzed in further studies. Because of the cellular interactions with the coating layers, it is likely that the results obtained are not caused by the underlying NiTi but due to the coating itself.

参考文献

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Surface Coating of NiTi Shape Memory Alloys with Calcium Phosphates by Dip-coating or Plasma-spraying-biological Characterization Examined by in vitro Testing Methods

参考文献