表面修饰Fe3O4磁性纳米粒子因具有优异的磁学特性、良好的生物相容性和丰富的化学反应可选择性,在生物医药领域如磁共振成像、组织修复、免疫测定、热疗、药物传递和细胞分离中显示了巨大的应用潜力.Fe3O4磁性纳米粒子的表面修饰主要包括以下3类:①有机小分子修饰,主要是偶联剂和表面活性剂修饰;②有机高分子修饰,包括天然生物大分子、合成高分子以及两者复合修饰;③无机纳米材料修饰,主要是SiO2、Au和Ag修饰.并就这三大方面的研究进展做了综合概述.
参考文献
| [1] | 李玉宝.纳米生物医药材料[M].北京:化学工业出版社,2004:141. |
| [2] | CUI Sheng,SHEN Xiaodong,LIN Benlan.Surface organic modification of Fe3O4 nanoparticles by silane-coupling agents[J].稀有金属（英文版）,2006(z1):426-430. |
| [3] | 谭家驹,张阳德,冯彦林,杨明,孙静,温广华,梁生,吴校连.一种新型生物-磁双重靶向纳米材料的制备[J].中国医学工程,2007(05):387-391. |
| [4] | Takami S;Sato T;Mousavand T et al.Hydrothermal synthesis of surface-modified iron oxide nanoDarticles[J].Materials Letters,2007,61:4769. |
| [5] | Zheng Y H;Cheng Y;Bao F et al.Synthesis and magnetic properties of Fe3O4 nanoparticles[J].Materials Research Bulletin,2006,41:525. |
| [6] | Shouheng Sun;Hao Zeng;David B. Robinson;Simone Raoux;Philip M. Rice;Shan X. Wang;Guanxiong Li .Monodisperse MFe_2O_4 (M = Fe, Co, Mn) Nanoparticles[J].Journal of the American Chemical Society,2004(1):273-279. |
| [7] | Yong Wang;Jian Feng Wong;Xiaowei Teng;Xue Zhang Lin;Hong Yang ."Pulling" Nanoparticles into Water: Phase Transfer of Oleic Acid Stabilized Monodisperse Nanoparticles into Aqueous Solutions of α-Cyclodextrin[J].Nano letters,2003(11):1555-1559. |
| [8] | 蒋新宇,周春山,张俊山,杨娟玉.导向药物用纳米Fe3O4磁性粒子的制备及表征[J].中南工业大学学报(自然科学版),2003(05):516-520. |
| [9] | 杨玉东,宋志伟,梁勇.有机盐制备的Fe3O4-葡聚糖纳米粒子的磁性能及表征[J].化学物理学报,2005(04):605-608. |
| [10] | 黄可龙,陈洁,刘素琴,李桂银.磁性Fe3O4/壳聚糖的化学修饰及包覆机理研究[J].无机化学学报,2007(08):1491-1495. |
| [11] | 夏金兰,廖鹏飞,聂珍媛,王晶,肖水明.羧甲基壳聚糖磁性纳米复合物的制备与表征[J].中南大学学报（自然科学版）,2006(06):1075-1080. |
| [12] | Ma HL;Qi XR;Maitani Y;Nagai T .Preparation and characterization of superparamagnetic iron oxide nanoparticles stabilized by alginate.[J].International Journal of Pharmaceutics,2007(1/2):177-186. |
| [13] | Liu T Y;Hua S H;Liu K H et al.Preparation and characterization of smart magnetic hydrogels and its use for drug release[J].Journal of Magnetism and Magnetic Materials,2006,304:397. |
| [14] | Saiyed ZM;Sharma S;Godawat R;Telang SD;Ramchand CN .Activity and stability of alkaline phosphatase (ALP) immobilized onto magnetic nanoparticles (Fe(3)O(4))[J].Journal of Biotechnology,2007(3):240-244. |
| [15] | Soenena S J H;Hodeniusb M;schmim R T et al.Proteinstabilized magnetic fluids[J].Journal of Magnetism and Magnetic Materials,2007,8:1. |
| [16] | Liu H L;Ko S P;Wu J H et al.One-pot polyol synthesis of monosize PVP-coated sub-5nm Fe3O4 nanoparticles for biomedical applications[J].Journal of Magnetism and Magnetic Materials,2007,310:815. |
| [17] | 熊隆荣,文玉华,易成,李宁.聚乙二醇-4000包覆Fe3O4磁流体的制备及稳定性研究[J].材料导报,2007(z1):195-197. |
| [18] | 魏珊珊,张艺,许家瑞.聚丙烯酸/Fe3O4纳米复合材料的制备及性能研究[J].中山大学学报（自然科学版）,2006(05):47-50. |
| [19] | 魏珊珊,祝亚非,张艺,许家瑞.聚（丙烯酸-丙烯酸羟乙酯）/Fe3O4磁流体的制备及表征[J].华东理工大学学报（自然科学版）,2006(06):634-637,671. |
| [20] | 刘学涌,常昆,王晓川,丁小斌,彭宇行.氨基两亲高分子磁性微球的制备与表征[J].高分子学报,2005(04):519-523. |
| [21] | Yang CL;Liu HZ;Guan YP;Xing JM;Liu JG;Shan GB .Preparation of magnetic poly(methylmethacrylate-divinylbenzene-glycidylmethacrylate) microspheres by spraying suspension polymerization and their use for protein adsorption[J].Journal of Magnetism and Magnetic Materials,2005(1):187-192. |
| [22] | Liu Z L;Ding Z H;Yao K L et al.Preparation and characterization of polymer-coated core-shell structured magnetic microbeads[J].Journal of Magnetism and Magnetic Materials,2003,265:98. |
| [23] | Liu Z L;Yang X B;Yao K L et al.Preparation and characterization of magnetic P(St-co-MAA-co-AM)microspheres[J].Journal of Magnetism and Magnetic Materials,2006,302:529. |
| [24] | Xu Z Z;Wang C C;Yang W L et al.Encapsulation of nanosized magnetic iron oxide by polyacrylamide via inverse miniemulsion polymerization[J].Journal of Magnetism and Magnetic Materials,2004,277:136. |
| [25] | 安丽娟,李兆强,徐娓,陈欣芳,杨柏.超顺磁性高分子微球的制备与表征[J].高等学校化学学报,2005(02):366-369. |
| [26] | 周春华,刘威,张书香,李辉,褚国红.Fe3O4/P（NaUA-St-BA）核-壳纳米磁性复合粒子的合成与表征[J].高分子学报,2005(04):606-610. |
| [27] | 陈志军,彭凯,方少明,田俊峰,李丁丁,贾陆军,冒小峰.Fe3O4表面原位引发可控/"活性"聚合制备磁性聚苯乙烯纳米粒子[J].物理化学学报,2007(03):349-354. |
| [28] | 张和鹏,张秋禹,王巍,罗绍兵,谢钢,张军平,王曙正.可控制自由基聚合DPE法制备P（AA-MMA-ST）/Fe3O4磁性复合微球[J].化学学报,2006(17):1831-1836. |
| [29] | 安丽娟,李兆强,王燕萍,杨柏.表面引发原子转移自由基聚合方法合成Fe3O4/PMMA复合纳米微粒[J].高等学校化学学报,2006(07):1372-1375. |
| [30] | Zhang J;Misra RD .Magnetic drug-targeting carrier encapsulated with thermosensitive smart polymer: core-shell nanoparticle carrier and drug release response.[J].Acta biomaterialia,2007(6):838-850. |
| [31] | Wu Y;Guo J;Yang WL;Wang CC;Fu SK .Preparation and characterization of chitosan-poly(acrylic acid) polymer magnetic microspheres[J].Polymer: The International Journal for the Science and Technology of Polymers,2006(15):5287-5294. |
| [32] | Zhang J;Rana S;Srivastava RS;Misra RD .On the chemical synthesis and drug delivery response of folate receptor-activated, polyethylene glycol-functionalized magnetite nanoparticles.[J].Acta biomaterialia,2008(1):40-48. |
| [33] | Hu FX;Neoh KG;Kang ET .Synthesis and in vitro anti-cancer evaluation of tamoxifen-loaded magnetite/PLLA composite nanoparticles[J].Biomaterials,2006(33):5725-5733. |
| [34] | 刘海弟,赵璇,陈运法.纳米磁性Fe3O4-SiO2复合材料的制备和表征[J].化学研究,2007(02):21-23,31. |
| [35] | 陈令允,李凤生,姜炜,王英会,周建.强磁性纳米Fe3O4/SiO2复合粒子的制备及其性能研究[J].材料科学与工程学报,2005(05):556-559,567. |
| [36] | Matjam Lohler;Glen E.Fryxell;Miqin Zhang .A Bifunctional Poly(ethylene glycol)Silane Immobilized on Metallic Oxide-Based Nanoparticles for Conjugation with Cell Targeting Agents[J].Journal of the American Chemical Society,2004(23):7206-7211. |
| [37] | Iglesias-Silva E;Rivas J;Isidro LML;Lopez-Quintela MA .Synthesis of silver-coated magnetite nanoparticles[J].Journal of Non-Crystalline Solids: A Journal Devoted to Oxide, Halide, Chalcogenide and Metallic Glasses, Amorphous Semiconductors, Non-Crystalline Films, Glass-Ceramics and Glassy Composites,2007(8/10):829-831. |
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