利用细菌纤维素超精细网络结构和高持水率的特点,在细菌纤维素上通过硼氢化钠(NaBH4)还原硝酸银中的Ag+原位生成纳米银颗粒,并对其微观结构等进行表征,同时对银负载细菌纤维素纳米复合膜的抗菌性能和生物相容性进行研究.XRD结果表明纳米银颗粒具有较完善的结晶结构,且银晶体为面心立方结构；XRF检测表明复合材料中含有Ag元素；由UV-Vis可知Ag/BC纳米复合材料在424nm处出现了Ag的吸收峰；从SEM图可看出随着硝酸银浓度的增大,细菌纤维素微纤表面负载的银颗粒增多,粒径大约为50～80nm.抗菌实验结果说明Ag/BC纳米复合材料具有很强的抗菌性能,对大肠杆菌和金黄色葡萄球菌的最大抑菌率分别达到99.4%和98.4%.细胞相容性实验表明,Ag/BC纳米复合材料还具有良好的细胞相容性.因此将其用于抗菌伤口敷料会有广阔的应用前景.
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