作为生物医用材料而言,由于聚乳酸本身的缺陷,制备具有生物活性的聚乳酸就成为一条可行的弥补之道.目前聚乳酸生物活化的方法有物理法和化学法.物理法主要通过共混、表面吸附或涂层等实现对聚乳酸的生物活化;化学法包括共聚、交联、表面修饰等,通过改变聚合物大分子或表面结构赋予材料生物活性.本文对这些方法进行了评述,并提出了采用仿生性设计原则来制备具有生物活性的聚乳酸材料.
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