采用沉淀-煅烧法制备了F掺杂HA的FHA(Ca_(10)(PO_4)_6(OH)_(2-2x)F_(2x),0≤x≤1)粉末.通过X射线衍射(XRD)、热重分析(TG)、高温膨胀仪,扫描电镜(SEM),能谱仪(EDS)以及模拟体液浸泡实验研究了F掺杂对FHA高温热稳定性,高温烧结性能,热膨胀系数和生物活性的影响.结果表明,F掺杂能够提高FHA的高温热稳定性,且随F掺杂量增加,其稳定性逐渐提高;少量F(x=0.25)掺杂提高了HA基体的烧结致密度,随F含量增加(x＞0.25),烧结致密度下降;F掺杂能降低FHA高温热膨胀系数(CET),随着F含量的增加,FHA的CET值减小.类骨磷灰石在块体表面的生长能力为FHA＞HA＞FA,其中x=0.5和0.75的FHA具有最好的生物活性.
FHA(Ca_(10)(PO_4)_6(OH)_(2-2x)F_(2x),0＜x＜1) powders were synthesized by wet precipitation-calcination method.XRD,TG,high-temperature dilatometer,SEM,EDS and SBF experiment were used to investigated the influences of F doping on the thermal stability and sintering properties of high temperature,thermal expansion coefficient,and bioactivity of FHA.The results show that doping F improves the thermal stability of FHA at high temperature,and the stability can be gradually improved with the inrease of F content;Sintering density of FHA bulk increases with small amount of F doping (x=0.25),but decreases when F doping content more than x=0.25.Thermal expansion coefficient(CET) of FHA decreases with the increase of F content.The growth ability of bone-like apatite forming on FHA bulk surface proved by the SBF soaking experiment is :FHA＞HA＞FA,and both F0.5HA and F0.75HA have the best bioactivity.
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