通过仿生自组装法在室温下制备了纳米碳酸化羟基磷灰石/胶原(nCHAC)复合材料,并借助X射线衍射(XRD)分析、热分析(TGA)和透射电镜(TEM)的观察对其进行了表征,结果表明:(1)该材料具有与天然骨相同的纳米尺度和胶原蛋白无机相,含有2.8%～14.7%(wt)的碳酸成分;(2)显微结构是矿化的胶原纤维束,类似于天然骨的分级结构.揭示了碳酸和胶原含量不同的复合材料中具有微小差别的自组装单元.碳酸的百分含量影响矿物的晶体尺寸和胶原纤维的组装.因此,nCHAC复合材料是有前途的硬组织修复用材料,这要归功于生物仿生制备出的材料具有与天然骨类似的成分和类似的微观结构.
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