Surface Characterization and Cell Response of Binary Ti-Ag Alloys with CP Ti as Material Control

材料科学技术（英文）, 2012, 28(9): 779-784.

Surface Characterization and Cell Response of Binary Ti-Ag Alloys with CP Ti as Material Control

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1.Center for Biomedical Materials and Engineering, Harbin Engineering University, Harbin 150001, China Department of Materials Science and Engineering, College of Engineering, Peking University, Beijing 100871, China

2.Center for Biomedical Materials and Engineering, Harbin Engineering University, Harbin 150001, China Department of Materials Science and Engineering, College of Engineering, Peking University, Beijing 100871, China

3.Center for Biomedical Materials and Engineering, Harbin Engineering University, Harbin 150001, China

4.Center for Biomedical Materials and Engineering, Harbin Engineering University, Harbin 150001, China

5.Center for Biomedical Materials and Engineering, Harbin Engineering University, Harbin 150001, China Department of Materials Science and Engineering, College of Engineering, Peking University, Beijing 100871, China

基金项目: the Re- search Fund for the Doctoral Program of Higher Educa- tion(20100001110011) Acknowledgements This work was supported by the National Basic Research Program of China(＂973 Program＂, . 2012CB619102 and 2012CB619100) the National High Technology Research and Development Program of China(＂863 Program＂, . 2011AA030101 and 2011AA030103) the National Natural Science Founda- tion of China(. 31170909 and 51041004) the Fundamental Research Funds for the Central Universities (No

关键词：细胞毒性试验 , 合金成分 , 表面特性 , CP , 材料控制 , 二进制 , X-射线光电子能谱 , 钛

Surface Characterization and Cell Response of Binary Ti-Ag Alloys with CP Ti as Material Control

Keywords： Ti-Ag alloy , Surfaces , Electrochemical corrosion , Cytotoxicity ,

In this study, the surface passive films, dissolution behavior and biocompatibility of Ti-Ag alloys (with 5%, 10% and 20% Ag) were evaluated by X-ray diffraction (XRD) tests, electrochemical corrosion tests, X-ray photoelectron spectroscopy (XPS) tests, dissolution tests and in-vitro cytotoxicity tests. The surface films on the Ti-20Ag alloy are rich in Ti and much deficient in Ag with respect to alloy composition, as identified by XPS. Compared to CP Ti, Ti-SAg and Ti-20Ag alloys show larger impedances and lower capacitances, which can be associated with an increase of the passive layer thickness. Moreover, all Ti-Ag alloys exhibit negligible or low metal release in the test solutions. The in-vitro cytotoxicity results show Ti-Ag alloys seem to be as cytocompatible as CP Ti. From the viewpoint of surface passive film and cytotoxicity, Ti-SAg and Ti-20Ag are considered to be more suitable for dental applications.

参考文献

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Surface Characterization and Cell Response of Binary Ti-Ag Alloys with CP Ti as Material Control

Surface Characterization and Cell Response of Binary Ti-Ag Alloys with CP Ti as Material Control

参考文献